6741期

最新文章

• Safety in the smoke AI翻译
  作者：Cornwall, Warren
• Equitable access needed in clinical research AI翻译
  作者：Dang, Gisa; Perrin, Christophe; Furin, Jennifer
  作者单位：Harvard University; Harvard Medical School
• High-frequency location data show that race affects citations and fines for speeding AI翻译
  作者：Aggarwal, Pradhi; Brandon, Alec; Goldszmidt, Ariel; Holz, Justin; List, John A.; Muir, Ian; Sun, Gregory; Yu, Thomas
  作者单位：Massachusetts Institute of Technology (MIT); Johns Hopkins University; University of Chicago; University of Michigan System; University of Michigan; Washington University (WUSTL); Yale University
  摘要：Prior research on racial profiling has found that in encounters with law enforcement, minorities are punished more severely than white civilians. Less is known about the causes of these encounters and their implications for our understanding of racial profiling. Using high-frequency location data of rideshare drivers in Florida (N = 222,838 individuals), we estimate the effect of driver race on citations and fines for speeding using 19.3 million location pings. Compared with a white driver tra...
• US cuts hamper disease surveillance worldwide AI翻译
  作者：Cohen, Jon
• How the World Eats: A Global Food Philosophy AI翻译
  作者：Pizzirani, Stefania
  作者单位：University of Fraser Valley; University of Fraser Valley
• Hedonic eating is controlled by dopamine neurons that oppose GLP-1R satiety AI翻译
  作者：Zhu, Zhenggang; Gong, Rong; Rodriguez, Vicente; Quach, Kathleen T.; Chen, Xinyu; Sternson, Scott M.
  作者单位：University of California System; University of California San Diego; Howard Hughes Medical Institute; Howard Hughes Medical Institute; University of California System; University of California San Diego; Beijing Normal University; Chinese Institute for Brain Research, Beijing
  摘要：Hedonic eating is defined as food consumption driven by palatability without physiological need. However, neural control of palatable food intake is poorly understood. We discovered that hedonic eating is controlled by a neural pathway from the peri-locus ceruleus to the ventral tegmental area (VTA). Using photometry-calibrated optogenetics, we found that VTA dopamine (VTADA) neurons encode palatability to bidirectionally regulate hedonic food consumption. VTADA neuron responsiveness was suppr...
• Running a genetic stop sign accelerates oxygen metabolism and energy production in horses AI翻译
  作者：Castiglione, Gianni M.; Chen, Xin; Xu, Zhenhua; Dbouk, Nadir H.; Bose, Anamika A.; Carmona-Berrio, David; Chi, Emiliana E.; Zhou, Lingli; Boronina, Tatiana N.; Cole, Robert N.; Wu, Shirley; Liu, Abby D.; Liu, Thalia D.; Lu, Haining; Kalbfleisch, Ted; Rinker, David; Rokas, Antonis; Ortved, Kyla; Duh, Elia J.
  作者单位：Vanderbilt University; Vanderbilt University; Johns Hopkins University; Vanderbilt University; Johns Hopkins University; University of Kentucky; University of Pennsylvania
  摘要：Horses are among nature's greatest athletes, yet the ancestral molecular adaptations fueling their energy demands are poorly understood. Within a clinically important pathway regulating redox and metabolic homeostasis (NRF2/KEAP1), we discovered an ancient mutation-conserved in all extant equids-that increases mitochondrial respiration while decreasing tissue-damaging oxidative stress. This mutation is a de novo premature opal stop codon in KEAP1 that is translationally recoded into a cysteine...
• Lined up for entanglement AI翻译
  作者：Moiseev, Evgeny; Wang, Kai
  作者单位：McGill University
  摘要：A framework widely used in classical contexts provides new insights into solving an important challenge in quantum technology
• Beyond hedonic eating AI翻译
  作者：Small, Dana M.
  作者单位：McGill University; McGill University; McGill University
• Mars rover detects long-chain carbon molecules AI翻译
  作者：Voosen, Paul
  摘要：Fatty acid byproducts that Curiosity found in an ancient lakebed could be the remains of microbes-or not