6749期

最新文章

• THE GHOST LAB AI翻译
  作者：Golbeck, Jennifer
  作者单位：University System of Maryland; University of Maryland College Park
• Safeguarding against biological weapons AI翻译
  作者：Ben Ouagrham-Gormley, Sonia
  作者单位：George Mason University
• Math and biology meet in the cerebellum: There can be surprising differences between what neurons do and what neurons cause AI翻译
  作者：Churchland, Mark M.; Sawtell, Nathaniel B.
  作者单位：Columbia University
• A vector calculus for neural computation in the cerebellum AI翻译
  作者：Fakharian, Mohammad Amin; Shoup, Alden M.; Hage, Paul; Elseweifi, Hisham Y.; Shadmehr, Reza
  作者单位：Johns Hopkins University; Johns Hopkins Medicine
  摘要：Null space theory predicts that neurons generate spikes not only to produce behavior but also to prevent the undesirable effect of other neurons on behavior. In this work, we show that this competitive cancellation is essential for understanding computation in the cerebellum. In marmosets, we identified a vector for each Purkinje cell (P cell) along which its spikes displaced the eyes. Two spikes in two different P cells produced superposition of their vectors. In the resulting population acti...
• Embracing bamboo's resilience AI翻译
  作者：Li, Longwei
  作者单位：Chuzhou University; Chuzhou University
• Brain drain or brain gain? Effects of high-skilled international emigration on origin countries AI翻译
  作者：Batista, Catia; Han, Daniel; Haushofer, Johannes; Khanna, Gaurav; McKenzie, David; Mobarak, Ahmed Mushfiq; Theoharides, Caroline; Yang, Dean
  作者单位：Universidade Nova de Lisboa; Boston University; Cornell University; Cornell University; University of California System; University of California San Diego; The World Bank; Yale University; Deakin University; Amherst College; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan
  摘要：How does emigration of highly educated citizens of low-income countries to high-income countries affect the economies of the origin countries? The direct effect is brain drain-a decrease in the country's human capital stock. However, there may also be indirect brain gain effects. This review summarizes evidence that uses causal inference methods to reveal mechanisms that may lead to brain drain, gain, or circulation. Collectively, the weight of the evidence suggests that migration opportunitie...
• Sequence-based prediction of intermolecular interactions driven by disordered regions AI翻译
  作者：Ginell, Garrett M.; Emenecker, Ryan J.; Lotthammer, Jeffrey M.; Keeley, Alex T.; Plassmeyer, Stephen P.; Razo, Nicholas; Usher, Emery T.; Pelham, Jaqueline F.; Holehouse, Alex S.
  作者单位：Washington University (WUSTL); Washington University (WUSTL)
  摘要：Intrinsically disordered regions (IDRs) in proteins play essential roles in cellular function. A growing body of work has shown that IDRs often interact with partners in a manner that does not depend on the precise order of amino acids but is instead driven by complementary chemical interactions, leading to disordered bound-state complexes. However, these chemically specific dynamic interactions are difficult to predict. In this study, we repurposed the chemical physics developed originally fo...
• Ancient Borrelia genomes document the evolutionary history of louse-borne relapsing fever AI翻译
  作者：Swali, Pooja; Booth, Thomas; Tan, Cedric C. S.; McCabe, Jesse; Anastasiadou, Kyriaki; Barrington, Christopher; Borrini, Matteo; Bricking, Adelle; Buckberry, Jo; Buster, Lindsey; Carlin, Rea; Gilardet, Alexandre; Glocke, Isabelle; Irish, Joel D.; Kelly, Monica; King, Megan; Petchey, Fiona; Peto, Jessica; Silva, Marina; Speidel, Leo; Tait, Frankie; Teoaca, Adelina; Valoriani, Satu; Williams, Mia; Madgwick, Richard; Mullan, Graham; Wilson, Linda; Cootes, Kevin; Armit, Ian; Gutierrez, Maximiliano G.; van Dorp, Lucy; Skoglund, Pontus
  作者单位：University of London; University College London; Francis Crick Institute; Francis Crick Institute; Liverpool John Moores University; University of Bradford; University of York - UK; Canterbury Christ Church University; Swedish Museum of Natural History; University of Waikato; University of Exeter; RIKEN; University of Reading; Cardiff University; University of Bristol; University of Bristol; Francis Crick Institute
  摘要：Several bacterial pathogens have transitioned from tick-borne to louse-borne transmission, which often involves genome reduction and increasing virulence. However, the timing of such transitions remains unclear. We sequenced four ancient Borrelia recurrentis genomes, the agent of louse-borne relapsing fever, dating from 2300 to 600 years ago. We estimated the divergence from its closest tick-borne relative to 6000 to 4000 years ago, which suggests an emergence coinciding with human lifestyle c...
• Directly visualizing the momentum-forbidden dark excitons and their dynamics in atomically thin semiconductors (vol 370, pg 1199, 2020) AI翻译
  作者：Madeo, Julien; Sahoo, Chakradhar; Campbell, Marshall; Pareek, Vivek; Wong, E. Laine; Al-Mahboob, Abdullah; Chan, Nicholas S.; Karmakar, Arka; Mariserla, Bala Murali Krishna; Li, Xiaoqin; Heinz, Tony F.; Cao, Ting; Dani, Keshav M.
• Pause deep-sea mining plans in Japan AI翻译
  作者：Liang, Mingrong; Khan, Shamshad Ahmed; Liang, Yuling; Chen, Defu; Song, Yunbo; Hong, Jingxin; Wang, Lei; Lu, Yongyue
  作者单位：South China Agricultural University; University of Hong Kong