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作者：Ortega-Jimenez, Victor M.; Kim, Dongjin; Kumar, Sunny; Kim, Changhwan; Koh, Je-Sung; Bhamla, Saad
作者单位：University of California System; University of California Berkeley; University of Maine System; University of Maine Orono; University System of Georgia; Georgia Institute of Technology; Ajou University
摘要：Rhagovelia ripple bugs use specialized middle-leg fans with a flat-ribbon architecture to navigate the surfaces of fast-moving streams. We show that the fan's directional stiffness enables fast, passive elastocapillary morphing, independent of muscle input. This flat-ribbon fan balances collapsibility during leg recovery with rigidity during drag-based propulsion, enabling full-body 96 degrees turns in 50 milliseconds, with forward speeds of up to 120 body lengths per second-on par with fruit ...
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作者：Wang, Chen; Rish, Anthony D.; Armbruster, Emily G.; Xie, Jiale; Loveland, Anna B.; Shen, Zhangfei; Gu, Bradley; Korostelev, Andrei A.; Pogliano, Joe; Fu, Tian-Min
作者单位：University of Massachusetts System; UMass Chan Medical School; University of Massachusetts Worcester; University of Massachusetts System; UMass Chan Medical School; University of Massachusetts Worcester; University of Massachusetts System; UMass Chan Medical School; University of Massachusetts Worcester; University System of Ohio; Ohio State University; University of California System; University of California San Diego
摘要：Retrons are antiphage defense systems that produce multicopy single-stranded DNA (msDNA) and hold promise for genome engineering. However, the mechanisms of defense remain unclear. The Retron-Septu system integrates retron and Septu antiphage defenses. Cryo-electron microscopy structures reveal asymmetric nucleoprotein complexes comprising a reverse transcriptase, msDNA (a hybrid of msdDNA and msrRNA), and two PtuAB copies. msdDNA and msrRNA are essential for assembling this complex, with msrR...
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作者：Yu, Qianhui; Kilik, Umut; Secchia, Stefano; Adam, Lukas; Tsai, Yu-Hwai; Fauci, Christiana; Janssens, Jasper; Childs, Charlie J.; Walton, Katherine D.; Lopez-Sandoval, Ruben; Wu, Angeline; Almato Bellavista, Marina; Huang, Sha; Steiner, Calen A.; Throm, Yannick; Boyle, Michael James; He, Zhisong; Beumer, Joep; Treutlein, Barbara; Lowe, Craig B.; Spence, Jason R.; Camp, J. Gray
作者单位：Roche Holding; University of Basel; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Michigan System; University of Michigan; Duke University; University of Colorado System; University of Colorado Anschutz; Yale University; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan
摘要：Diet, microbiota, and other exposures make the intestinal epithelium a nexus for evolutionary change; however, little is known about genomic changes associated with adaptation to a distinctly human environment. In this work, we interrogate the evolution of cell types in the developing human intestine by comparing tissue and organoids from humans, chimpanzees, and mice. We find that recent changes in primates are associated with immune barrier function and lipid and xenobiotic metabolism and th...
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作者：Aubin, Cameron A.
作者单位：University of Michigan System; University of Michigan
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作者：Nair, Hari Ram C. R.
作者单位：Chalmers University of Technology
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作者：Sala, Giacomo; Mercaldo, Maria Teresa; Domi, Klevis; Gariglio, Stefano; Cuoco, Mario; Ortix, Carmine; Caviglia, Andrea D.
作者单位：University of Geneva; University of Salerno; Consiglio Nazionale delle Ricerche (CNR); University of Salerno; Istituto Superconduttori, Materiali e Dispositivi Innovativi (SPIN-CNR)
摘要：Quantum materials are characterized by electromagnetic responses intrinsically linked to the geometry and topology of electronic wavefunctions that are encoded in the quantum metric and Berry curvature. Whereas Berry curvature-mediated transport effects have been identified in several magnetic and nonmagnetic systems, quantum metric-induced transport phenomena remain limited to topological antiferromagnets. Here, we show that spin-momentum locking, a general characteristic of the electronic st...
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作者：Turekian, Vaughan C.; Gluckman, Peter
作者单位：National Academies of Sciences, Engineering & Medicine
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作者：Villanea, Fernando A.; Peede, David; Kaufman, Eli J.; Anorve-Garibay, Valeria; Chevy, Elizabeth T.; Villa-Islas, Viridiana; Witt, Kelsey E.; Zeloni, Roberta; Marnetto, Davide; Moorjani, Priya; Jay, Flora; Valdmanis, Paul N.; Avila-Arcos, Maria C.; Huerta-Sanchez, Emilia
作者单位：University of Colorado System; University of Colorado Boulder; Brown University; Brown University; Brown University; University of Washington; University of Washington Seattle; Universidad Nacional Autonoma de Mexico; University of Copenhagen; Clemson University; Clemson University; University of Padua; University of Turin; University of California System; University of California Berkeley; University of California System; University of California Berkeley; Inria; Universite Paris Saclay; Microsoft; Centre National de la Recherche Scientifique (CNRS); Trinity College Dublin; Brown University
摘要：We study the gene MUC19, for which some modern humans carry a Denisovan-like haplotype. MUC19 is a mucin, a glycoprotein that forms gels with various biological functions. We find diagnostic variants for the Denisovan-like MUC19 haplotype at high frequencies in admixed American individuals and at highest frequency in 23 ancient Indigenous American individuals, all pre-dating population admixture with Europeans and Africans. We find that the Denisovan-like MUC19 haplotype is under positive sele...
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作者：Cornwall, Warren
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作者：Wolf, Leslie E.; Kench, Samantha; Gross, Marielle
作者单位：University System of Georgia; Georgia State University; University System of Georgia; Georgia State University; University System of Georgia; Augusta University; University System of Georgia; Georgia State University; Johns Hopkins University; Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple University
