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作者：Park, See-On; Hong, Seokman; Sung, Su-Jin; Kim, Dawon; Seo, Seokho; Jeong, Hakcheon; Park, Taehoon; Cho, Won Joon; Kim, Jeehwan; Choi, Shinhyun
作者单位：Korea Advanced Institute of Science & Technology (KAIST); Samsung Electronics; Samsung; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT)
摘要：Phase-change memory (PCM) has been considered a promising candidate for solving von Neumann bottlenecks owing to its low latency, non-volatile memory property and high integration density1,2. However, PCMs usually require a large current for the reset process by melting the phase-change material into an amorphous phase, which deteriorates the energy efficiency2-5. Various studies have been conducted to reduce the operation current by minimizing the device dimensions, but this increases the fab...
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作者：Turon, Gemma; Njoroge, Mathew; Mulubwa, Mwila; Duran-Frigola, Miquel; Chibale, Kelly
作者单位：University of Cape Town; University of Cape Town
摘要：Computational models that require very little data could transform biomedical and drug development research in Africa, as long as infrastructure, trained staff and secure databases are available.
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作者：Tufan, Turan; Comertpay, Gamze; Villani, Ambra; Nelson, Geoffrey M.; Terekhova, Marina; Kelley, Shannon; Zakharov, Pavel; Ellison, Rochelle M.; Shpynov, Oleg; Raymond, Michael; Sun, Jerry; Chen, Yitan; Bockelmann, Enno; Stremska, Marta; Peterson, Lance W.; Boeckaerts, Laura; Goldman, Seth R.; Etchegaray, J. Iker; Artyomov, Maxim N.; Peri, Francesca; Ravichandran, Kodi S.
作者单位：Washington University (WUSTL); University of Zurich; Harvard University; Harvard Medical School; University of Virginia; University of Virginia; Washington University (WUSTL); Flanders Institute for Biotechnology (VIB); Ghent University; Ghent University
摘要：During development, inflammation or tissue injury, macrophages may successively engulf and process multiple apoptotic corpses via efferocytosis to achieve tissue homeostasis1. How macrophages may rapidly adapt their transcription to achieve continuous corpse uptake is incompletely understood. Transcriptional pause/release is an evolutionarily conserved mechanism, in which RNA polymerase (Pol) II initiates transcription for 20-60 nucleotides, is paused for minutes to hours and is then released ...
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作者：Chowdhury, Rumman
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作者：Dolgin, Elie
摘要：Drug trial results show that vaccines aren't the only use for the mRNA technology behind the most widely used COVID-19 jabs.
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作者：Wen, Xingzhao; Luo, Zhifei; Zhao, Wenxin; Calandrelli, Riccardo; Nguyen, Tri C.; Wan, Xueyi; Richard, John Lalith Charles; Zhong, Sheng
作者单位：University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego
摘要：Dynamically organized chromatin complexes often involve multiplex chromatin interactions and sometimes chromatin-associated RNA 1-3 . Chromatin complex compositions change during cellular differentiation and ageing, and are expected to be highly heterogeneous among terminally differentiated single cells 4-7 . Here we introduce the multinucleic acid interaction mapping in single cells (MUSIC) technique for concurrent profiling of multiplex chromatin interactions, gene expression and RNA-chromat...
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作者：Eddy, Sean R.
作者单位：Harvard University; Harvard University; Howard Hughes Medical Institute
摘要：In experiments dubbed the Random Genome Project, researchers have integrated DNA strands with random sequences into yeast and mouse cells to find the default transcriptional state of their genomes.
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作者：[Anonymous]
摘要：Applying a 'base editor' allows cells to crank out increased levels of a vital metabolic enzyme.
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作者：Liu, Shunchang; Lu, Yue; Yu, Cao; Li, Jia; Luo, Ran; Guo, Renjun; Liang, Haoming; Jia, Xiangkun; Guo, Xiao; Wang, Yu-Duan; Zhou, Qilin; Wang, Xi; Yang, Shaofei; Sui, Manling; Mueller-Buschbaum, Peter; Hou, Yi
作者单位：National University of Singapore; National University of Singapore; Beijing University of Technology; Technical University of Munich; Technical University of Munich
摘要：Perovskite bandgap tuning without quality loss makes perovskites unique among solar absorbers, offering promising avenues for tandem solar cells1,2. However, minimizing the voltage loss when their bandgap is increased to above 1.90 eV for triple-junction tandem use is challenging3-5. Here we present a previously unknown pseudohalide, cyanate (OCN-), with a comparable effective ionic radius (1.97 angstrom) to bromide (1.95 angstrom) as a bromide substitute. Electron microscopy and X-ray scatter...
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作者：Montag, Christian; Becker, Benjamin
作者单位：Ulm University; University of Hong Kong
