作者：[Anonymous]
摘要：All around the world, people are pushing back against racism, gender bias and other forms of discrimination to make a positive difference. Our series will tell their stories and highlight their achievements.
作者：Adam, Jose M.; Makoond, Nirvan; Riveiro, Belen; Buitrago, Manuel
作者单位：Universitat Politecnica de Valencia; Universidade de Vigo
摘要：Hundreds of millions of people cross deficient bridges each day. With damage to these structures likely to intensify because of climate change and ageing, technicians and policymakers must act to make them safer.
作者：Abraham, Jean E.; Pinilla, Karen; Dayimu, Alimu; Grybowicz, Louise; Demiris, Nikolaos; Harvey, Caron; Drewett, Lynsey M.; Lucey, Rebecca; Fulton, Alexander; Roberts, Anne N.; Worley, Joanna R.; Chhabra, Anita; Qian, Wendi; Vallier, Anne-Laure; Hardy, Richard M.; Chan, Steve; Hickish, Tamas; Tripathi, Devashish; Venkitaraman, Ramachandran; Persic, Mojca; Aslam, Shahzeena; Glassman, Daniel; Raj, Sanjay; Borley, Annabel; Braybrooke, Jeremy P.; Sutherland, Stephanie; Staples, Emma; Scott, Lucy C.; Davies, Mark; Palmer, Cheryl A.; Moody, Margaret; Churn, Mark J.; Newby, Jacqueline C.; Mukesh, Mukesh B.; Chakrabarti, Amitabha; Roylance, Rebecca R.; Schouten, Philip C.; Levitt, Nicola C.; Mcadam, Karen; Armstrong, Anne C.; Copson, Ellen R.; Mcmurtry, Emma; Tischkowitz, Marc; Provenzano, Elena; Earl, Helena M.
作者单位：University of Cambridge; Cancer Research UK; University of Cambridge; CRUK Cambridge Institute; University of Cambridge; University of Cambridge; Athens University of Economics & Business; University of Cambridge; University of Cambridge; Nottingham University Hospital NHS Trust; University of Nottingham; Russells Hall Hospital; Ipswich Hospital NHS Trust; Pinderfields Hospital; University of Southampton; University Hospital Southampton NHS Foundation Trust; Velindre Cancer Centre; Mount Vernon Cancer Centre; Beatson Oncology Centre; University of London; University College London; Royal Free London NHS Foundation Trust; University of London; University College London; University College London Hospitals NHS Foundation Trust; Cambridge University Hospitals NHS Foundation Trust; Addenbrooke's Hospital; University of Cambridge; Oxford University Hospitals NHS Foundation Trust; University of Manchester; Christie NHS Foundation Trust; University of Southampton; University of Cambridge
摘要：PARTNER is a prospective, phase II-III, randomized controlled clinical trial that recruited patients with triple-negative breast cancer(1,2), who were germline BRCA1 and BRCA2 wild type(3). Here we report the results of the trial. Patients (n = 559) were randomized on a 1:1 basis to receive neoadjuvant carboplatin-paclitaxel with or without 150 mg olaparib twice daily, on days 3 to 14, of each of four cycles (gap schedule olaparib, research arm) followed by three cycles of anthracycline-based ...
作者：Yang, Lin; Yue, Shengying; Tao, Yi; Qiao, Shuo; Li, Hang; Dai, Zhaohe; Song, Bai; Chen, Yunfei; Du, Jinlong; Li, Deyu; Gao, Peng
作者单位：Peking University; Xi'an Jiaotong University; Southeast University - China; Southeast University - China; Peking University; Peking University; Peking University; Vanderbilt University; Peking University
摘要：Nanoscale structures can produce extreme strain that enables unprecedented material properties, such as tailored electronic bandgap(1-5), elevated superconducting temperature(6,7) and enhanced electrocatalytic activity(8,9). While uniform strains are known to elicit limited effects on heat flow(10-15), the impact of inhomogeneous strains has remained elusive owing to the coexistence of interfaces(16-20) and defects(21-23). Here we address this gap by introducing inhomogeneous strain through be...
