8032期

最新文章

• Controlled patterning of crystalline domains by frontal polymerization AI翻译
  作者：Paul, Justine E.; Gao, Yuan; Go, Yoo Kyung; Koett, Luis E. Rodriguez; Sharma, Anisha; Chen, Manxin; Lessard, Jacob J.; Topkaya, Tolga; Leal, Cecilia; Moore, Jeffrey S.; Geubelle, Philippe H.; Sottos, Nancy R.
  作者单位：University of Illinois System; University of Illinois Urbana-Champaign; University of Illinois System; University of Illinois Urbana-Champaign; University of Illinois System; University of Illinois Urbana-Champaign; Huazhong University of Science & Technology; University of Illinois System; University of Illinois Urbana-Champaign; Batman University
  摘要：Materials with hierarchical architectures that combine soft and hard material domains with coalesced interfaces possess superior properties compared with their homogeneous counterparts(1-4). These architectures in synthetic materials have been achieved through deterministic manufacturing strategies such as 3D printing, which require an a priori design and active intervention throughout the process to achieve architectures spanning multiple length scales(5-9). Here we harness frontal polymeriza...
• Brain gain: how volunteer scientists are fact-checking the professionals AI翻译
  作者：[Anonymous]
• High-performers and specialists in neuroscience research AI翻译
  作者：[Anonymous]
  摘要：An overview of the countries and institutions that dedicate a high proportion of their research to neuroscience.
• Space radiation measurements during the Artemis I lunar mission AI翻译
  作者：George, Stuart P.; Gaza, Ramona; Matthiae, Daniel; Laramore, Diego; Lehti, Jussi; Campbell-Ricketts, Thomas; Kroupa, Martin; Stoffle, Nicholas; Marsalek, Karel; Przybyla, Bartos; Abdelmelek, Mena; Aeckerlein, Joachim; Bahadori, Amir A.; Barzilla, Janet; Dieckmann, Matthias; Ecord, Michael; Egeland, Ricky; Eronen, Timo; Fry, Dan; Jones, Bailey H.; Hellweg, Christine E.; Houri, Jordan; Hirsh, Robert; Hirvonen, Mika; Hovland, Scott; Hussein, Hesham; Johnson, A. Steve; Kasemann, Moritz; Lee, Kerry; Leitgab, Martin; McLeod, Catherine; Milstein, Oren; Pinsky, Lawrence; Quinn, Phillip; Riihonen, Esa; Rohde, Markus; Rozhdestvenskyy, Sergiy; Saari, Jouni; Schram, Aaron; Straube, Ulrich; Turecek, Daniel; Virtanen, Pasi; Waterman, Gideon; Wheeler, Scott; Whitman, Kathryn; Wirtz, Michael; Vandewalle, Madelyn; Zeitlin, Cary; Semones, Edward; Berger, Thomas
  作者单位：National Aeronautics & Space Administration (NASA); NASA Johnson Space Center; Helmholtz Association; German Aerospace Centre (DLR); European Space Agency; European Space Research & Technology Centre; University of Houston System; University of Houston; European Space Agency; United States Department of Energy (DOE); Los Alamos National Laboratory; Kansas State University; Aerospace Corporation - USA; Abbott Laboratories
  摘要：Space radiation is a notable hazard for long-duration human spaceflight(1). Associated risks include cancer, cataracts, degenerative diseases(2) and tissue reactions from large, acute exposures(3). Space radiation originates from diverse sources, including galactic cosmic rays4, trapped-particle (Van Allen) belts(5) and solar-particle events(6). Previous radiation data are from the International Space Station and the Space Shuttle in low-Earth orbit protected by heavy shielding and Earth's mag...
• Sympathetic neuropeptide Y protects from obesity by sustaining thermogenic fat AI翻译
  作者：Zhu, Yitao; Yao, Lu; Gallo-Ferraz, Ana L.; Bombassaro, Bruna; Simoes, Marcela R.; Abe, Ichitaro; Chen, Jing; Sarker, Gitalee; Ciccarelli, Alessandro; Zhou, Linna; Lee, Carl; Sidarta-Oliveira, Davi; Martinez-Sanchez, Noelia; Dustin, Michael L.; Zhan, Cheng; Horvath, Tamas L.; Velloso, Licio A.; Kajimura, Shingo; Domingos, Ana I.
  作者单位：University of Oxford; Universidade Estadual de Campinas; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Beth Israel Deaconess Medical Center; Oita University; Beijing Sport University; Francis Crick Institute; University of Oxford; Ludwig Institute for Cancer Research; University of Oxford; Kennedy Institute for Rheumatology; University of Oxford; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Yale University
  摘要：Human mutations in neuropeptide Y (NPY) have been linked to high body mass index but not altered dietary patterns1. Here we uncover the mechanism by which NPY in sympathetic neurons2,3 protects from obesity. Imaging of cleared mouse brown and white adipose tissue (BAT and WAT, respectively) established that NPY+ sympathetic axons are a smaller subset that mostly maps to the perivasculature; analysis of single-cell RNA sequencing datasets identified mural cells as the main NPY-responsive cells ...
• Essential vector-disease resource faces shutdown without funding AI翻译
  作者：Christophides, George K.
  作者单位：Imperial College London
• Neuronal wiring diagram of an adult brain AI翻译
  作者：Dorkenwald, Sven; Matsliah, Arie; Sterling, Amy R.; Schlegel, Philipp; Yu, Szi-chieh; Mckellar, Claire E.; Lin, Albert; Costa, Marta; Eichler, Katharina; Yin, Yijie; Silversmith, Will; Schneider-Mizell, Casey; Jordan, Chris S.; Brittain, Derrick; Halageri, Akhilesh; Kuehner, Kai; Ogedengbe, Oluwaseun; Morey, Ryan; Gager, Jay; Kruk, Krzysztof; Perlman, Eric; Yang, Runzhe; Deutsch, David; Bland, Doug; Sorek, Marissa; Lu, Ran; Macrina, Thomas; Lee, Kisuk; Bae, J. Alexander; Mu, Shang; Nehoran, Barak; Mitchell, Eric; Popovych, Sergiy; Wu, Jingpeng; Jia, Zhen; Castro, Manuel A.; Kemnitz, Nico; Ih, Dodam; Bates, Alexander Shakeel; Eckstein, Nils; Funke, Jan; Collman, Forrest; Bock, Davi D.; Jefferis, Gregory S. X. E.; Seung, H. Sebastian; Murthy, Mala
  作者单位：Princeton University; Princeton University; MRC Laboratory Molecular Biology; University of Cambridge; Princeton University; Allen Institute for Brain Science; University of Haifa; Massachusetts Institute of Technology (MIT); Princeton University; Harvard University; Harvard Medical School; University of Oxford; Howard Hughes Medical Institute; University of Vermont
  摘要：Connections between neurons can be mapped by acquiring and analysing electron microscopic brain images. In recent years, this approach has been applied to chunks of brains to reconstruct local connectivity maps that are highly informative1-6, but nevertheless inadequate for understanding brain function more globally. Here we present a neuronal wiring diagram of a whole brain containing 5 x 107 chemical synapses7 between 139,255 neurons reconstructed from an adult female Drosophila melanogaster...
• How long COVID could lift the fog on neurocognitive disorders AI翻译
  作者：Peluso, Michael J.; Ely, E. Wesley
  作者单位：University of California System; University of California San Francisco; Vanderbilt University
• The fly connectome reveals a path to the effectome AI翻译
  作者：Pospisil, Dean A.; Aragon, Max J.; Dorkenwald, Sven; Matsliah, Arie; Sterling, Amy R.; Schlegel, Philipp; Yu, Szi-chieh; McKellar, Claire E.; Costa, Marta; Eichler, Katharina; Jefferis, Gregory S. X. E.; Murthy, Mala; Pillow, Jonathan W.
  作者单位：Princeton University; Princeton University; MRC Laboratory Molecular Biology; University of Cambridge
  摘要：A goal of neuroscience is to obtain a causal model of the nervous system. The recently reported whole-brain fly connectome1-3 specifies the synaptic paths by which neurons can affect each other, but not how strongly they do affect each other in vivo. To overcome this limitation, we introduce a combined experimental and statistical strategy for efficiently learning a causal model of the fly brain, which we refer to as the 'effectome'. Specifically, we propose an estimator for a linear dynamical...
• Bronze Age clash was Europe's oldest known interregional battle AI翻译
  作者：[Anonymous]
  摘要：Artefacts found in modern-day Germany suggest that northern and southern peoples clashed in the Tollense Valley millennia ago.