作者:Garisto, Dan
摘要:The University of Rochester has confirmed that it no longer employs Ranga Dias, who was found by investigators to have fabricated data.
作者:Hwang, Sung-Min; Awasthi, Deepika; Jeong, Jieun; Sandoval, Tito A.; Chae, Chang-Suk; Ramos, Yusibeska; Tan, Chen; Falco, Matias Marin; Salvagno, Camilla; Emmanuelli, Alexander; McBain, Ian T.; Mishra, Bikash; Ivashkiv, Lionel B.; Zamarin, Dmitriy; Cantillo, Evelyn; Chapman-Davis, Eloise; Holcomb, Kevin; Morales, Diana K.; Yu, Xiaoqing; Rodriguez, Paulo C.; Conejo-Garcia, Jose R.; Kaczocha, Martin; Vaharautio, Anna; Song, Minkyung; Cubillos-Ruiz, Juan R.
作者单位:Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Memorial Sloan Kettering Cancer Center; University of Helsinki; Cornell University; Icahn School of Medicine at Mount Sinai; H Lee Moffitt Cancer Center & Research Institute; Duke University; Duke University; State University of New York (SUNY) System; Stony Brook University; Stony Brook University Hospital; State University of New York (SUNY) System; Stony Brook University; State University of New York (SUNY) System; Stony Brook University; Stony Brook University Hospital; National Cancer Center - Korea (NCC); Sungkyunkwan University (SKKU); Sungkyunkwan University (SKKU)
摘要:Mounting effective immunity against pathogens and tumours relies on the successful metabolic programming of Tcells by extracellular fatty acids(1-3). Fatty-acid-binding protein5 (FABP5) has a key role in this process by coordinating the efficient import and trafficking of lipids that fuel mitochondrial respiration to sustain the bioenergetic requirements of protective CD8(+) Tcells(4,5). However, the mechanisms that govern this immunometabolic axis remain unexplored. Here we report that the cy...
作者:Wen, John H.; Sorscher, Ben; Jones, Emily A. Aery; Ganguli, Surya; Giocomo, Lisa M.
作者单位:Stanford University; Stanford University; Stanford University; Howard Hughes Medical Institute
摘要:Animals must navigate changing environments to find food, shelter or mates. In mammals, grid cells in the medial entorhinal cortex construct a neural spatial map of the external environment1-5. However, how grid cell firing patterns rapidly adapt to novel or changing environmental features on a timescale relevant to behaviour remains unknown. Here, by recording over 15,000 grid cells in mice navigating virtual environments, we tracked the real-time state of the grid cell network. This allowed ...