8071期

最新文章

• First samples from the Moon's 'dark side' AI翻译
  作者：Elardo, Stephen M.
  作者单位：State University System of Florida; University of Florida
• The subfornical organ is a nucleus for gut-derived T cells that regulate behaviour AI翻译
  作者：Yoshida, Tomomi M.; Nguyen, Mytien; Zhang, Le; Lu, Benjamin Y.; Zhu, Biqing; Murray, Katie N.; Mineur, Yann S.; Zhang, Cuiling; Xu, Di; Lin, Elizabeth; Luchsinger, Joseph; Bhatta, Sagar; Waizman, Daniel A.; Coden, Mackenzie E.; Ma, Yifan; Israni-Winger, Kavita; Russo, Anthony; Wang, Haowei; Song, Wenzhi; Al Souz, Jafar; Zhao, Hongyu; Craft, Joseph E.; Picciotto, Marina R.; Grutzendler, Jaime; Distasio, Marcello; Palm, Noah W.; Hafler, David A.; Wang, Andrew
  作者单位：Yale University; Yale University; Yale University; Yale University; Yale University; Yale University; Yale University; Yale University; Yale University; Yale University
  摘要：Specialized immune cells that reside in tissues orchestrate diverse biological functions by communicating with parenchymal cells1. The contribution of the innate immune compartment in the meninges and the central nervous system (CNS) is well-characterized; however, whether cells of the adaptive immune system reside in the brain and are involved in maintaining homeostasis is unclear2, 3-4. Here we show that the subfornical organ (SFO) of the brain is a nucleus for parenchymal alpha beta T cells...
• How monitoring a remote Finnish peatland helps climate science AI翻译
  作者：Martinelli, Francesco; Taipale, Risto
• Obesity drugs made in China could power next wave of treatments AI翻译
  作者：Fieldhouse, Rachel
• Regulatory genomic circuitry of human disease loci by integrative epigenomics (vol 590, pg 300, 2021) AI翻译
  作者：Boix, Carles A.; James, Benjamin T.; Park, Yongjin P.; Meuleman, Wouter; Kellis, Manolis
• Science on the catwalk: Iris van Herpen gives gowns a glow up AI翻译
  作者：Spinney, Laura
• Bioinspired capillary force-driven super-adhesive filter AI翻译
  作者：Park, Junyong; Moon, Chan Sik; Lee, Ji Min; Rahat, Sazzadul A.; Kim, Sang Moon; Pham, Jonathan T.; Kappl, Michael; Butt, Hans-Juergen; Wooh, Sanghyuk
  作者单位：Chung Ang University; University System of Ohio; University of Cincinnati; Incheon National University; University System of Ohio; University of Cincinnati; Max Planck Society
  摘要：Capturing particles with low, nanonewton-scale adhesion is an ongoing challenge for conventional air filters1,2. Inspired by the natural filtration abilities of mucus-coated nasal hairs3,4, we introduce an efficient, biomimetic filter that exploits a thin liquid coating. Here we show that a stable thin liquid layer is formed on several filter media that generates enhanced particulate adhesion, driven by micronewton to sub-micronewton capillary forces5,6. Enhanced particle adhesion increases th...
• Human de novo mutation rates from a four-generation pedigree reference AI翻译
  作者：Porubsky, David; Dashnow, Harriet; Sasani, Thomas A.; Logsdon, Glennis A.; Hallast, Pille; Noyes, Michelle D.; Kronenberg, Zev N.; Mokveld, Tom; Koundinya, Nidhi; Nolan, Cillian; Steely, Cody J.; Guarracino, Andrea; Dolzhenko, Egor; Harvey, William T.; Rowell, William J.; Grigorev, Kirill; Nicholas, Thomas J.; Goldberg, Michael E.; Oshima, Keisuke K.; Lin, Jiadong; Ebert, Peter; Watkins, W. Scott; Leung, Tiffany Y.; Hanlon, Vincent C. T.; McGee, Sean; Pedersen, Brent S.; Happ, Hannah C.; Jeong, Hyeonsoo; Munson, Katherine M.; Hoekzema, Kendra; Chan, Daniel D.; Wang, Yanni; Knuth, Jordan; Garcia, Gage H.; Fanslow, Cairbre; Lambert, Christine; Lee, Charles; Smith, Joshua D.; Levy, Shawn; Mason, Christopher E.; Garrison, Erik; Lansdorp, Peter M.; Neklason, Deborah W.; Jorde, Lynn B.; Quinlan, Aaron R.; Eberle, Michael A.; Eichler, Evan E.
  作者单位：University of Washington; University of Washington Seattle; Utah System of Higher Education; University of Utah; University of Colorado System; University of Colorado Anschutz Medical Campus; Jackson Laboratory; University of Kentucky; University of Tennessee System; University of Tennessee Health Science Center; National Aeronautics & Space Administration (NASA); NASA Ames Research Center; University of Pennsylvania; Heinrich Heine University Dusseldorf; Heinrich Heine University Dusseldorf; Heinrich Heine University Dusseldorf Hospital; Heinrich Heine University Dusseldorf; British Columbia Cancer Agency; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; University of British Columbia; Howard Hughes Medical Institute; University of Washington; University of Washington Seattle
  摘要：Understanding the human de novo mutation (DNM) rate requires complete sequence information1. Here using five complementary short-read and long-read sequencing technologies, we phased and assembled more than 95% of each diploid human genome in a four-generation, twenty-eight-member family (CEPH 1463). We estimate 98-206 DNMs per transmission, including 74.5 de novo single-nucleotide variants, 7.4 non-tandem repeat indels, 65.3 de novo indels or structural variants originating from tandem repeat...
• Poo of farm animals teems with drug-resistance genes AI翻译
  作者：[Anonymous]
• An open AI model could help medical experts to interpret chest X-rays AI翻译
  作者：Kim, Namkug
  作者单位：University of Ulsan; University of Ulsan