作者：Jaleh, Babak; Eslamipanah, Mahtab
作者单位：Bu Ali Sina University
作者：van Huis, Arnold; Gasco, Laura
作者单位：Wageningen University & Research; University of Turin
作者：Seo, Dong-oh; 'Donnell, David; Jain, Nimansha; Ulrich, Jason D.; Herz, Jasmin; Li, Yuhao; Lemieux, Mackenzie; Cheng, Jiye; Hu, Hao; Serrano, Javier R.; Bao, Xin; Franke, Emily; Karlsson, Maria; Meier, Martin; Deng, Su; Desai, Chandani; Dodiya, Hemraj; Lelwala-Guruge, Janaki; Handley, Scott A.; Kipnis, Jonathan; Sisodia, Sangram S.; Gordon, Jeffrey I.; Holtzman, David M.
作者单位：Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); University of Chicago; Washington University (WUSTL)
摘要：Tau-mediated neurodegeneration is a hallmark of Alzheimer's disease. Primary tauopathies are characterized by pathological tau accumulation and neuronal and synaptic loss. Apolipoprotein E (ApoE)-mediated neuroinflammation is involved in the progression of tau-mediated neurodegeneration, and emerging evidence suggests that the gut microbiota regulates neuroinflammation in an APOE genotype-dependent manner. However, evidence of a causal link between the microbiota and tau -mediated neurodegener...
作者：Jain, Tanya; Li, Yue-Ming
作者单位：Memorial Sloan Kettering Cancer Center; Cornell University; Cornell University
摘要：Microbiota mediate neuroinflammation in a genetic-and sex-specific manner in mice
