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作者：Thorp, H. Holden
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作者：Pownall, Mark E.; Miao, Liyun; Vejnar, Charles E.; M'Saad, Ons; Sherrard, Alice; Frederick, Megan A.; Benitez, Maria D. J.; Boswell, Curtis W.; Zaret, Kenneth S.; Bewersdorf, Joerg; Giraldez, Antonio J.
作者单位：Yale University; Yale University; Yale University; University of Pennsylvania; Yale University; Yale University; Yale University; Yale University; Yale University; Yale New Haven Hospital
摘要：Nanoscale chromatin organization regulates gene expression. Although chromatin is notably reprogrammed during zygotic genome activation (ZGA), the organization of chromatin regulatory factors during this universal process remains unclear. In this work, we developed chromatin expansion microscopy (ChromExM) to visualize chromatin, transcription, and transcription factors in vivo. ChromExM of embryos during ZGA revealed how the pioneer factor Nanog interacts with nucleosomes and RNA polymerase I...
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作者：Chin, Xin Yu; Turkay, Deniz; Steele, Julian A.; Tabean, Saba; Eswara, Santhana; Mensi, Mounir; Fiala, Peter; Wolff, Christian M.; Paracchino, Adriana; Artuk, Kerem; Jacobs, Daniel; Guesnay, Quentin; Sahli, Florent; Andreatta, Gaelle; Boccard, Mathieu; Jeangros, Quentin; Ballif, Christophe
作者单位：Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Swiss Center for Electronics & Microtechnology (CSEM); KU Leuven; University of Queensland; University of Queensland; Luxembourg Institute of Science & Technology; University of Luxembourg; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
摘要：Silicon solar cells are approaching their theoretical efficiency limit of 29%. This limitation can be exceeded with advanced device architectures, where two or more solar cells are stacked to improve the harvesting of solar energy. In this work, we devise a tandem device with a perovskite layer conformally coated on a silicon bottom cell featuring micrometric pyramids-the industry standard-to improve its photocurrent. Using an additive in the processing sequence, we regulate the perovskite cry...
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作者：Kilburg-Basnyat, Brita
摘要：Idon't think industry would be a good fit for me, the student said, I'm not money-motivated. As an industry scientist myself, I struggled to hide my surprise. I was participating in a conference event to help graduate students and postdocs explore career options by connecting with professionals across industry, academia, government, and nonprofits. I love my work, and I was excited to share it with the attendees. Overall, they were enthusiastic to learn about their options, and some were seri...
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作者：Thaiss, Christoph A.
作者单位：University of Pennsylvania
摘要：Gut-brain connections drive the motivation to work out Exercise is arguably the most potent and attainable lifestyle factor that individuals can use to safeguard themselves against a large variety of diseases, including metabolic, cardiovascular, neurodegenerative, and neoplastic diseases (1). Despite its vast health benefits, only a small fraction of the population adheres to the World Health Organization's recommendation of 150 to 300 minutes of moderate-intensity exercise per week (2). Busy...
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作者：Heidt, Amanda
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作者：Brainard, Jeffrey
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作者：Hannibal, Mary Ellen
摘要：A new documentary series traces humanity's profound effects on the world around us
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作者：Clasen, Sara
作者单位：Max Planck Society
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作者：Goldy, Camila; Caillaud, Marie-Cecile
作者单位：Centre National de la Recherche Scientifique (CNRS); Ecole Normale Superieure de Lyon (ENS de LYON); Universite Claude Bernard Lyon 1; INRAE
摘要：Promoting asymmetric division through microtubule dynamics establishes cell fate In multicellular organisms, cell division contributes to the generation of specialized cells. In walled organisms such as plants, the orientation of the division plane by which two daughter cells separate is of special importance because cells are embedded in a matrix and cannot relocate. To define the future cell division zone before mitosis, plants have evolved a specific structure called the preprophase band (P...
