Nature

最新文章

• 'Powerful and horrifying' - David Attenborough's latest film is a cry to protect our oceans AI翻译
  作者：Simms, Chris
• Black hole flings out clumps of gas AI翻译
  作者：Bischetti, Manuela
  作者单位：University of Trieste
• Bulk-spatiotemporal vortex correspondence in gyromagnetic zero-index media AI翻译
  作者：Zhang, Ruo-Yang; Cui, Xiaohan; Zeng, Yuan-Song; Chen, Jin; Liu, Wenzhe; Wang, Mudi; Wang, Dongyang; Zhang, Zhao-Qing; Wang, Neng; Wu, Geng-Bo; Chan, C. T.
  作者单位：Hong Kong University of Science & Technology; City University of Hong Kong; City University of Hong Kong; Fudan University; Wuhan University; Wuhan University; University of Southampton; Shenzhen University; Hong Kong University of Science & Technology
  摘要：Photonic double-zero-index media, distinguished by concurrently zero-valued permittivity and permeability, exhibit extraordinary properties not found in nature1, 2, 3, 4, 5, 6, 7-8. Notably, the notion of zero index can be substantially expanded by generalizing the constitutive parameters from null scalars to non-reciprocal tensors with non-zero matrix elements but zero determinants9,10. Here we experimentally realize this class of gyromagnetic double-zero-index metamaterials possessing both d...
• Cell cycle duration determines oncogenic transformation capacity AI翻译
  作者：Chen, Danian; Lu, Suying; Huang, Katherine; Pearson, Joel D.; Pacal, Marek; Peidis, Phillipos; Mccurdy, Sean; Yu, Tao; Sangwan, Monika; Nguyen, Angela; Monnier, Philippe P.; Schramek, Daniel; Zhu, Liang; Santamaria, David; Barbacid, Mariano; Akeno, Nagako; Wikenheiser-Brokamp, Kathryn A.; Bremner, Rod
  作者单位：University of Toronto; Sinai Health System Toronto; Lunenfeld Tanenbaum Research Institute; University of Toronto; University of Toronto; Sichuan University; University of Toronto; University Health Network Toronto; Krembil Research Institute; University of Toronto; Yeshiva University; Montefiore Medical Center; Albert Einstein College of Medicine; Yeshiva University; Montefiore Medical Center; Albert Einstein College of Medicine; Yeshiva University; Montefiore Medical Center; Albert Einstein College of Medicine; Yeshiva University; Montefiore Medical Center; Albert Einstein College of Medicine; University of Salamanca; Consejo Superior de Investigaciones Cientificas (CSIC); Cincinnati Children's Hospital Medical Center; Cincinnati Children's Hospital Medical Center; University System of Ohio; University of Cincinnati; University of Manitoba; University of Manitoba
  摘要：Oncogenic mutations are widespread in normal human tissues(1). Similarly, in murine chimeras, cells carrying an oncogenic lesion contribute normal cells to adult tissues without causing cancer(2,3,4). How lineages that escape cancer via normal development differ from the minority that succumb is unclear. Tumours exhibit characteristic cancer hallmarks; we therefore searched for hallmarks that differentiate cancer-prone lineages from resistant lineages. Here we show that total cell cycle durati...
• End-to-end data-driven weather prediction AI翻译
  作者：Allen, Anna; Markou, Stratis; Tebbutt, Will; Requeima, James; Bruinsma, Wessel P.; Andersson, Tom R.; Herzog, Michael; Lane, Nicholas D.; Chantry, Matthew; Hosking, J. Scott; Turner, Richard E.
  作者单位：University of Cambridge; University of Cambridge; University of Toronto; Vector Institute for Artificial Intelligence; UK Research & Innovation (UKRI); Natural Environment Research Council (NERC); NERC British Antarctic Survey; University of Cambridge; European Centre for Medium-Range Weather Forecasts (ECMWF); Alan Turing Institute; Alphabet Inc.; DeepMind; Google Incorporated
  摘要：Weather prediction is critical for a range of human activities, including transportation, agriculture and industry, as well as for the safety of the general public. Machine learning transforms numerical weather prediction (NWP) by replacing the numerical solver with neural networks, improving the speed and accuracy of the forecasting component of the prediction pipeline1, 2, 3, 4, 5-6. However, current models rely on numerical systems at initialization and to produce local forecasts, thereby l...
• Telescope team reads the fine print - from more than a kilometre away AI翻译
  作者：[Anonymous]
• Psychedelic control of neuroimmune interactions governing fear AI翻译
  作者：Chung, Elizabeth N.; Lee, Jinsu; Polonio, Carolina M.; Choi, Joshua; Akl, Camilo Faust; Kilian, Michael; Weiss, Wiebke M.; Gunner, Georgia; Ye, Mingyu; Heo, Tae Hyun; Drake, Sienna S.; Yang, Liu; d'Eca, Catarina R. G. L.; Lee, Joon-Hyuk; Deng, Liwen; Farrenkopf, Daniel; Schuele, Anton M.; Lee, Hong-Gyun; Afolabi, Oreoluwa; Ghaznavi, Sharmin; Smirnakis, Stelios M.; Chiu, Isaac M.; Kuchroo, Vijay K.; Quintana, Francisco J.; Wheeler, Michael A.
  作者单位：Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Brigham & Women's Hospital; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard Medical School; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute
  摘要：Neuroimmune interactions-signals transmitted between immune and brain cells-regulate many aspects of tissue physiology1, including responses to psychological stress2, 3, 4-5, which can predispose individuals to develop neuropsychiatric diseases6, 7, 8-9. Still, the interactions between haematopoietic and brain-resident cells that influence complex behaviours are poorly understood. Here, we use a combination of genomic and behavioural screens to show that astrocytes in the amygdala limit stress...
• Plasticity of the mammalian integrated stress response AI翻译
  作者：Chen, Chien-Wen; Papadopoli, David; Szkop, Krzysztof J.; Guan, Bo-Jhih; Alzahrani, Mohammed; Wu, Jing; Jobava, Raul; Asraf, Mais M.; Krokowski, Dawid; Vourekas, Anastasios; Merrick, William C.; Komar, Anton A.; Koromilas, Antonis E.; Gorospe, Myriam; Payea, Matthew J.; Wang, Fangfang; Clayton, Benjamin L. L.; Tesar, Paul J.; Schaffer, Ashleigh; Miron, Alexander; Bederman, Ilya; Jankowsky, Eckhard; Vogel, Christine; Valasek, Leos Shivaya; Dinman, Jonathan D.; Zhang, Youwei; Tirosh, Boaz; Larsson, Ola; Topisirovic, Ivan; Hatzoglou, Maria
  作者单位：University System of Ohio; Case Western Reserve University; Lady Davis Institute; Jewish General Hospital - Montreal; McGill University; Karolinska Institutet; University System of Ohio; Case Western Reserve University; King Saud Bin Abdulaziz University for Health Sciences; Yale University; Maria Curie-Sklodowska University; Louisiana State University System; Louisiana State University; University System of Ohio; Cleveland State University; McGill University; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA); University System of Ohio; Case Western Reserve University; University System of Ohio; Case Western Reserve University; New York University; Czech Academy of Sciences; Institute of Microbiology of the Czech Academy of Sciences; University System of Maryland; University of Maryland College Park; University System of Maryland; University of Maryland Baltimore; Universities at Shady Grove; McGill University
  摘要：An increased level of phosphorylation of eukaryotic translation initiation factor 2 subunit-alpha (eIF2 alpha, encoded by EIF2S1; eIF2 alpha-p) coupled with decreased guanine nucleotide exchange activity of eIF2B is a hallmark of the 'canonical' integrated stress response (c-ISR)1. It is unclear whether impaired eIF2B activity in human diseases including leukodystrophies2, which occurs in the absence of eIF2 alpha-p induction, is synonymous with the c-ISR. Here we describe a mechanism triggere...
• Radiative forcing reduced by early twenty-first century increase in land albedo AI翻译
  作者：Hou, Zhengyang; Zhang, Liqiang; Peng, Jingjing; Forzieri, Giovanni; Jia, Aolin; Xiao, Zhiqiang; Qu, Ying; Lin, Jintai; Ji, Duoying; Zhu, Zidong; Yao, Xin; Peng, Shuwen; Zhao, Lanpu; Fan, Wenjie; Wu, Zhaocong; Geng, Hao; Wang, Qihao; Zhou, Chenghu; Liu, Suhong; Zhang, Liangpei
  作者单位：Beijing Normal University; Henan Academy of Sciences; University System of Maryland; University of Maryland College Park; University of Florence; Luxembourg Institute of Science & Technology; Peking University; Peking University; Peking University; Chinese Academy of Sciences; Institute of Geographic Sciences & Natural Resources Research, CAS
  摘要：Surface albedo greatly affects how much energy the Earth absorbs. Intensive human activities and accelerated climate change have altered surface albedo across spatial and temporal scales(1, 2-3), yet assessments of the effects of land use or land cover (LULC) and snow variations on land surface albedo are scarce at the global scale. As a result, the global land surface albedo dynamics over recent decades and their corresponding radiative forcing to the climate system remain poorly understood(4...
• World first: ultra-powerful CRISPR treatment trialled in a person AI翻译
  作者：Ledford, Heidi
  摘要：Immune-cell function improved in a teenager whose DNA was altered using prime editing.