6768期

最新文章

• Ancient alleles drive contemporary climate adaptation in an alpine plant AI翻译
  作者：Fior, Simone; Luqman, Hirzi; Scharmann, Mathias; Palsson, Aksel; de Jonge, Jennifer; Zoller, Stefan; Zemp, Niklaus; Gargano, Domenico; Wegmann, Daniel; Widmer, Alex
  作者单位：Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Cambridge; University of Bayreuth; Swedish University of Agricultural Sciences; Swedish University of Agricultural Sciences; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Calabria; University of Fribourg; Swiss Institute of Bioinformatics
  摘要：Adaptive evolution is key for species to persist in a warming climate. However, how adaptive genetic variants arise and shape both past and future evolutionary trajectories remains largely unknown. In this work, we integrate genomics with functional and ecological assays to unravel the evolutionary history and adaptive potential of alleles governing adaptation to climate through flowering time in an Alpine carnation. We reveal that warm and cold alleles of the flowering inhibitor CENTRORADIALI...
• Replaceable You: Adventures in Human Anatomy AI翻译
  作者：Kemp, Christopher
  作者单位：Michigan State University
• Marine origins and freshwater radiations of the otophysan fishes AI翻译
  作者：Liu, Juan; Brinkman, Donald B.; Murray, Alison M.; Newbrey, Michael G.; Zhou, Zehua; Van Loon, Lisa L.; Banerjee, Neil R.
  作者单位：University of California System; University of California Berkeley; University of California System; University of California Berkeley; University of Alberta; University System of Georgia; Columbus State University; Michigan State University; Western University (University of Western Ontario); Western University (University of Western Ontario)
  摘要：Otophysans, known for their enhanced hearing enabled by the complex Weberian apparatus, comprise two-thirds of extant freshwater fish species. Previously, they were thought to have originated in fresh water before the breakup of Pangea, implying a nearly 80-million-year gap between the origin and oldest known fossil. However, the discovery of a Late Cretaceous freshwater otophysan challenges this view. Integrating fossil, morphological, and genomic data, we estimate a younger crown group origi...
• Upwelling that lasted millions of years AI翻译
  作者：Rosenthal, Yair; Hess, Anya V.
  作者单位：Rutgers University System; Rutgers University New Brunswick; Rutgers University System; Rutgers University New Brunswick; George Mason University
• A high-resolution molecular spin-photon interface at telecommunication wavelengths AI翻译
  作者：Weiss, Leah R.; Smith, Grant T.; Murphy, Ryan A.; Golesorkhi, Bahman; Mendez Mendez, Jose A.; Patel, Priya; Niklas, Jens; Poluektov, Oleg G.; Long, Jeffrey R.; Awschalom, David D.
  作者单位：University of Chicago; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; United States Department of Energy (DOE); Argonne National Laboratory; University of California System; University of California Berkeley; University of California System; University of California Berkeley; University of Chicago; United States Department of Energy (DOE); Argonne National Laboratory; United States Department of Energy (DOE); Argonne National Laboratory
  摘要：Optically addressable electronic spins in polyatomic molecules are a promising platform for quantum information science, with the potential to enable scalable qubit design and integration through atomistic tunability and nanoscale localization. However, optical state- and site-selection are an open challenge. In this work, we introduce an organo-erbium spin qubit in which narrow (megahertz-scale) optical and spin transitions couple to provide high-resolution access to spin degrees of freedom w...
• A lesson in mentoring AI翻译
  作者：Yaqub, Muneer
  作者单位：University of Texas System; University of Texas Dallas
• Battery charging goes quantum AI翻译
  作者：Warburton, Robert E.
  作者单位：University System of Ohio; Case Western Reserve University
• Wildfire management at a crossroads: Mitigation and prevention or response and recovery? AI翻译
  作者：Gray, Robert; Gregory, Robin; Sandborn, Calvin
  作者单位：University of British Columbia; Oregon Research Institute; University of Victoria
• Ambitious collaboration will map primate brains-including ours-in unprecedented detail AI翻译
  作者：Stone, Richard
• GCN1 couples GCN2 to ribosomal state to initiate amino acid response pathway signaling AI翻译
  作者：Zhou, Changqian; Zhang, Miao; Murray, Jason; Paulo, Joao; Gygi, Steve; Shao, Sichen; Whitman, Malcolm; Keller, Tracy
  作者单位：Harvard University; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard Medical School; Howard Hughes Medical Institute
  摘要：During nutrient deprivation, activation of the protein kinase GCN2 regulates cell survival and metabolic homeostasis. In addition to amino acid stress, GCN2 is activated by a variety of cellular stresses. GCN2 activation has been linked to its association with uncharged tRNAs, specific ribosomal proteins, and conditions of translational arrest, but their relative contribution to activation is unclear. Here, we used in vitro translation to reconstitute GCN2 activation by amino acid stress and c...