作者：BECKER, NG; MARSCHNER, IC
摘要：Using a multiplicative model, the age-specific relative risk of infection with the human immunodeficiency virus, HIV, and the time-dependent HIV infection rate can be estimated simultaneously from acquired immunodeficiency syndrome, AIDS, incidence data. Non-parametric estimates are arrived at by an EM-algorithm, with smoothing, applied to a back-projection model. The method gives estimates which lie on a smooth curve in accordance with strong prior expectations. The approach is illustrated wi...
