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作者：Lee, SJ; Kim, K; Tsiatis, AA
作者单位：University of Michigan System; University of Michigan; Harvard University; Harvard T.H. Chan School of Public Health
摘要：When longitudinal clinical trials are monitored, multiplicity from repeated significance testing as well as from repeated measures has to be accounted for properly to control the overall type I error. This often involves a multidimensional integration procedure to compute group sequential boundaries. We establish an independent increments structure of sequentially computed test statistics based on the generalised estimating equations of Liang & Zeger (1986) for longitudinal data. This simplifi...
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作者：Box, G; Tyssedal, J
摘要：A question of importance in factor screening is when a two-level orthogonal design for a multifactor experiment can be projected into lower dimension, typically P=2 or 3. New results relate to the projectivity P of saturated designs in which n - 1 factors are tested in n runs. It is shown that: a design obtained by 'doubling' an n x n orthogonal array is always of projectivity P = 2; a two-level cyclic design is either a factorial array, and hence has P = 2, or it has P = 3; a two-level orthog...
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作者：Kwan, ACC; Sim, AB
作者单位：University of New South Wales Sydney
摘要：This paper proposes three modified portmanteau tests based on the applications of the Fisher (1921) and Hotelling (1953) transformations to sample autocorrelations. The test statistics are asymptotically chi-square. Our simulation results indicate that the empirical significance levels of the proposed tests are more reliable than the portmanteau tests of Box & Pierce (1970), Ljung & Box (1978) and Dufour & Roy (1986) when the sample size is small (15 less than or equal to n less than or equal ...
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作者：Pfanzagl, J; Sheynin, O
摘要：The t-distribution first occurred in a paper by Luroth (1876) on the classical theory of errors in connection with a Bayesian result.
