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作者：Johnson, WO
作者单位：University of California System; University of California Davis
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作者：Reilly, C; Wang, CC; Rutherford, M
作者单位：University of Minnesota System; University of Minnesota Twin Cities; University of Minnesota System; University of Minnesota Twin Cities; University of Minnesota System; University of Minnesota Twin Cities
摘要：One of the more challenging, yet easily overlooked, aspects of the analysis of microarrays is how to normalize arrays so that comparisons can be made across arrays. Most studies that utilize microarrays to detect differential gene expression between samples find the data only enable one to conclude that a handful of genes are differentially expressed. The basic idea here is to use the genes that are not differentially expressed to conduct the normalization. Of course, because one cannot determ...
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作者：Tarpey, T; Petkova, E; Ogden, RT
作者单位：University System of Ohio; Wright State University Dayton; Columbia University
摘要：Identification of placebo responders among subjects treated with active drug has significant clinical and research implications. In clinical practice, when a patient treated with medication improves, this improvement may be attributed to the chemical component of the drug itself, a placebo effect, or some combination of these. Determining the proper subsequent treatment and maintenance of the patient may be greatly aided by understanding the mechanism of patient improvement. In a research cont...
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作者：Hjort, NL; Claeskens, G
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作者：Schoenberg, FP
作者单位：University of California System; University of California Los Angeles
摘要：Residual analysis methods for examining the fit of multidimensional point process models are applied to point process models for the space-time-magnitude distribution of earthquake occurrences, using, in particular, the multidimensional version of Ogata's epidemic-type aftershock sequence (ETAS) model and a 30-year catalog of 580 earthquakes occurring in Bear Valley, California. One method involves rescaled residuals, obtained by transforming points along one coordinate to form a homogeneous P...
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作者：Tsai, CL
作者单位：University of California System; University of California Davis
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作者：Cottet, R; Smith, M
作者单位：University of Sydney
摘要：The advent of wholesale electricity markets has brought renewed focus on intraday electricity load forecasting. This article proposes a multiequation regression model with a diagonal first-order stationary vector autoregresson (VAR) for modeling and forecasting intraday electricity load. The correlation structure of the disturbances to the VAR and the appropriate subset of regressors are explored using Bayesian model selection methodology. The full spectrum of finite-sample inference is obtain...
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作者：Ishwaran, H; Rao, JS
作者单位：Cleveland Clinic Foundation; University System of Ohio; Case Western Reserve University
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作者：Clements, A; Hurn, S; Lindsay, K
作者单位：Queensland University of Technology (QUT); University of Glasgow
摘要：It is well known that the manipulation of sample data by means of a parametric function can improve the performance of kernel density estimation. This article proposes a two-parameter Mobius-like function to map sample data drawn from a semi-infinite space into [-1, 1). A standard kernel method is then used to estimate the density. The proposed method is shown to yield effective estimates of density and is computationally more efficient than other well-known transformation methods. The efficac...
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作者：Hjort, NL; Claeskens, G
作者单位：University of Oslo; Texas A&M University System; Texas A&M University College Station
摘要：The traditional use of model selection methods in practice is to proceed as if the final selected model had been chosen in advance, without acknowledging the additional uncertainty introduced by model selection. This often means underreporting of variability and too optimistic confidence intervals. We build a general large-sample likelihood apparatus in which limiting distributions and risk properties of estimators post-selection as well as of model average estimators are precisely described, ...
