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作者：Schoenberg, FP
作者单位：University of California System; University of California Los Angeles
摘要：Residual analysis methods for examining the fit of multidimensional point process models are applied to point process models for the space-time-magnitude distribution of earthquake occurrences, using, in particular, the multidimensional version of Ogata's epidemic-type aftershock sequence (ETAS) model and a 30-year catalog of 580 earthquakes occurring in Bear Valley, California. One method involves rescaled residuals, obtained by transforming points along one coordinate to form a homogeneous P...
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作者：Tsai, CL
作者单位：University of California System; University of California Davis
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作者：Suchard, MA; Weiss, RE; Sinsheimer, JS; Dorman, KS; Patel, M; McCabe, ERB
作者单位：University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; Iowa State University; Iowa State University; University of Toronto; Hospital for Sick Children (SickKids); University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA
摘要：An evolutionary history of a set of organisms is a family tree, or topology, with branches of various lengths between vertices that describe how closely the organisms are related to each other. We consider the K evolutionary histories of K genes from a set of N organisms. Evolutionary similarity (ES) occurs when the branching patterns and relative branch lengths in the K evolutionary histories of the genes are the same or nearly the same across the set of organisms. Evolutionary similarity ind...
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作者：Tzeng, JY; Byerley, W; Devlin, B; Roeder, K; Wasserman, L
作者单位：Carnegie Mellon University; University of California System; University of California Irvine; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Western Psychiatric Institute & Clinic of UPMC
摘要：We define a statistic, called the matching statistic, for locating regions of the genome that exhibit excess similarity among cases when compared to controls. Such regions are reasonable candidates for harboring disease genes. We find the asymptotic distribution of the statistic while accounting for correlations among sampled individuals. We then use the Benjamini and Hochberg false discovery rate (FDR) method for multiple hypothesis testing to find regions of excess sharing. The p values for ...
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作者：Cottet, R; Smith, M
作者单位：University of Sydney
摘要：The advent of wholesale electricity markets has brought renewed focus on intraday electricity load forecasting. This article proposes a multiequation regression model with a diagonal first-order stationary vector autoregresson (VAR) for modeling and forecasting intraday electricity load. The correlation structure of the disturbances to the VAR and the appropriate subset of regressors are explored using Bayesian model selection methodology. The full spectrum of finite-sample inference is obtain...
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作者：Gelfand, AE; Kim, HJ; Sirmans, CF; Banerjee, S
作者单位：Duke University; University of Oulu; University of Connecticut; University of Minnesota System; University of Minnesota Twin Cities
摘要：In many applications, the objective is to build regression models to explain a response variable over a region of interest under the assumption that the responses are spatially correlated. In nearly all of this work, the regression coefficients are assumed to be constant over the region. However, in some applications, coefficients are expected to vary at the local or subregional level. Here we focus on the local case. Although parametric modeling of the spatial surface for the coefficient is p...
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作者：Landrum, MB; Normand, SLT; Rosenheck, RA
作者单位：Harvard University; Harvard Medical School; Harvard University; Harvard T.H. Chan School of Public Health; Yale University
摘要：Quantitative performance monitoring of health care providers has become an increasingly prominent activity in health care delivery. As a consequence, multidimensional report cards comparing the quality of services provided by diverse health care organizations have begun to appear. We present a case study examining the performance of 22 geographically defined health care systems, known as Veterans Integrated Service Networks; involving the treatment of more than 37,000 veterans discharged from ...
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作者：Ishwaran, H; Rao, JS
作者单位：Cleveland Clinic Foundation; University System of Ohio; Case Western Reserve University
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作者：Javaras, KN; Van Dyk, DA
作者单位：University of Oxford; University of California System; University of California Irvine
摘要：We consider the application of multiple imputation to data containing not only partially missing categorical and continuous variables, but also partially missing 'semicontinuous' variables (variables that take on a single discrete value with positive probability but are otherwise continuously distributed). As an imputation model for data sets of this type, we introduce an extension of the standard general location model proposed by Olkin and Tate; our extension, the blocked general location mo...
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作者：Morris, JS; Vannucci, M; Brown, PJ; Carroll, RJ
作者单位：University of Texas System; UTMD Anderson Cancer Center; Texas A&M University System; Texas A&M University College Station; University of Kent; Texas A&M University System; Texas A&M University College Station
摘要：In this article we develop new methods for analyzing the data from an experiment using rodent models to investigate the effect of type of dietary fat on O-6-methylguanine-DNA-methyltransferase (MGMT), an important biomarker in early colon carcinogenesis. The data consist of observed profiles over a spatial variable contained within a two-stage hierarchy, a structure that we dub hierarchical functional data. We present a new method providing a unified framework for modeling these data, simultan...
