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作者：Paciorek, Christopher J.; McLachlan, Jason S.
作者单位：Harvard University; Harvard T.H. Chan School of Public Health; University of Notre Dame
摘要：Ecologists use the relative abundance of fossil pollen tit sediments to estimate how tree species abundances change over space and time. To predict historical forest composition and quantify the available information, we build a Bayesian hierarchical model of forest composition in central New England, USA. based oil pollen in a network of ponds. The critical relationships between abundances of taxa in the pollen record and abundances as actual vegetation are estimated for the modern and coloni...
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作者：Witten, Daniela M.; Hastie, Trevor; Tibshirani, Robert
作者单位：Stanford University; Stanford University
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作者：Rueda, Cristina; Fernandez, Miguel A.; Das Peddada, Shyamal
作者单位：Universidad de Valladolid; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS)
摘要：Motivated by a problem encountered in the analysis of cell cycle gene expression data. this article deals with the estimation of parameters subject to order restrictions on a unit circle. A normal eukaryotic cell cycle has four major phases, during cell division, and a cell cycle gene has its peak expression (phase angle) during the phase that may correspond to its biological function. Because the phases are ordered along a circle, the phase angles of cell cycle genes are ordered unknown param...
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作者：Park, Byeong U.; Mammen, Enno; Haerdle, Wolfgang; Borak, Szymon
作者单位：Seoul National University (SNU); University of Mannheim; Humboldt University of Berlin
摘要：High-dimensional regression problems, which reveal dynamic behavior, are typically analyzed by time propagation of a few number of factors. The inference on the whole system is then based on the low-dimensional time series analysis. Such high-dimensional problems occur frequently in many different fields of science. In this article we address the problem of inference when the factors and factor loadings are estimated by semiparametric methods. This more flexible modeling approach poses an impo...
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作者：Boldea, Otilia; Magnus, Jan R.
作者单位：Tilburg University
摘要：The Hessian of the multivariate normal mixture model is derived, and estimators of the information matrix are obtained, thus enabling consistent estimation of all parameters and their precisions. The usefulness of the new theory is illustrated with two examples and some simulation experiments. The newly proposed estimators appear to be superior to the existing ones.
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作者：Hilbe, Joseph M.
作者单位：Arizona State University
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作者：Wang, Zuoheng; McPeek, Mary Sara
作者单位：University of Chicago; University of Chicago
摘要：We propose an incomplete-data, quasi-likelihood framework for estimation and score tests that accommodates both dependent and partially observed data. The motivation comes from genetic association studies, where we address the problems of estimating haplotype frequencies and testing association between a disease and haplotypes of multiple. tightly linked genetic markers, using case-control samples containing, related individuals. We consider a more general setting in which the complete data ar...
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作者：Bartolucci, Francesco; Farcomeni, Alessio
作者单位：University of Perugia; Sapienza University Rome
摘要：For the analysis of multivariate categorical longitudinal data, we propose an extension of the dynamic logit model. The resulting model is based oil a marginal parameterization of the conditional distribution of each vector of response variables given the covariates, the lagged response variables. and a set of subject-specific parameters for the unobserved heterogeneity. The latter ones are assumed to follow a first-order Markov chain. For the maximum likelihood estimation of the model paramet...
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作者：Johnstone, Iain M.; Lu, Arthur Yu
作者单位：Stanford University
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作者：Rosenbaum, Paul R.; Silber, Jeffrey H.
作者单位：University of Pennsylvania; University of Pennsylvania
摘要：In randomized experiments, it is sometimes important to demonstrate that two treatments do not differ greatly in their effects, or to demonstrate that the treatments have very different effects on one outcome similar effects on another outcome. These demonstrations may take the form of rejecting a null hypothesis of inequivalence in an equivalence test, or rejecting a null hypothesis of equal and inequivalent effects on two outcomes. The procedures often express a complex hypothesis in terms o...
