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作者：Leng, Ling
作者单位：Amazon.com
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作者：Crawford, Lorin; Monod, Anthea; Chen, Andrew X.; Mukherjee, Sayan; Rabadan, Raul
作者单位：Brown University; Brown University; Brown University; Tel Aviv University; Columbia University; Duke University; Duke University; Duke University; Duke University
摘要：Glioblastoma multiforme (GBM) is an aggressive form of human brain cancer that is under active study in the field of cancer biology. Its rapid progression and the relative time cost of obtaining molecular data make other readily available forms of data, such as images, an important resource for actionable measures in patients. Our goal is to use information given by medical images taken from GBM patients in statistical settings. To do this, we design a novel statistic?the smooth Euler characte...
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作者：Robin, Genevieve; Klopp, Olga; Josse, Julie; Moulines, Eric; Tibshirani, Robert
作者单位：Institut Polytechnique de Paris; Ecole Polytechnique; Inria; ESSEC Business School; Institut Polytechnique de Paris; ENSAE Paris; HSE University (National Research University Higher School of Economics); Stanford University; Stanford University
摘要：A mixed data frame (MDF) is a table collecting categorical, numerical, and count observations. The use of MDF is widespread in statistics and the applications are numerous from abundance data in ecology to recommender systems. In many cases, an MDF exhibits simultaneously main effects, such as row, column, or group effects and interactions, for which a low-rank model has often been suggested. Although the literature on low-rank approximations is very substantial, with few exceptions, existing ...
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作者：Guan, Qian; Reich, Brian J.; Laber, Eric B.; Bandyopadhyay, Dipankar
作者单位：North Carolina State University; Virginia Commonwealth University
摘要：Tooth loss from periodontal disease is a major public health burden in the United States. Standard clinical practice is to recommend a dental visit every six months; however, this practice is not evidence-based, and poor dental outcomes and increasing dental insurance premiums indicate room for improvement. We consider a tailored approach that recommends recall time based on patient characteristics and medical history to minimize disease progression without increasing resource expenditures. We...
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作者：McAlinn, Kenichiro; Aastveit, Knut Are; Nakajima, Jouchi; West, Mike
作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple University; Duke University; Norges Bank; BI Norwegian Business School; Bank of Japan
摘要：We present new methodology and a case study in use of a class of Bayesian predictive synthesis (BPS) models for multivariate time series forecasting. This extends the foundational BPS framework to the multivariate setting, with detailed application in the topical and challenging context of multistep macroeconomic forecasting in a monetary policy setting. BPS evaluates?sequentially and adaptively over time?varying forecast biases and facets of miscalibration of individual forecast densities for...
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作者：Fogarty, Colin B.
作者单位：Massachusetts Institute of Technology (MIT)
摘要：A fundamental limitation of causal inference in observational studies is that perceived evidence for an effect might instead be explained by factors not accounted for in the primary analysis. Methods for assessing the sensitivity of a study's conclusions to unmeasured confounding have been established under the assumption that the treatment effect is constant across all individuals. In the potential presence of unmeasured confounding, it has been argued that certain patterns of effect heteroge...
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作者：Guan, Yawen; Johnson, Margaret C.; Katzfuss, Matthias; Mannshardt, Elizabeth; Messier, Kyle P.; Reich, Brian J.; Song, Joon J.
作者单位：North Carolina State University; Texas A&M University System; Texas A&M University College Station; United States Environmental Protection Agency; Oregon State University; Baylor University; University of Nebraska System; University of Nebraska Lincoln; National Aeronautics & Space Administration (NASA); NASA Jet Propulsion Laboratory (JPL); California Institute of Technology
摘要：People are increasingly concerned with understanding their personal environment, including possible exposure to harmful air pollutants. To make informed decisions on their day-to-day activities, they are interested in real-time information on a localized scale. Publicly available, fine-scale, high-quality air pollution measurements acquired using mobile monitors represent a paradigm shift in measurement technologies. A methodological framework utilizing these increasingly fine-scale measuremen...
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作者：Shi, Chengchun; Lu, Wenbin; Song, Rui
作者单位：North Carolina State University
摘要：In contrast to the classical one-size-fits-all approach, precision medicine proposes the customization of individualized treatment regimes to account for patients' heterogeneity in response to treatments. Most of existing works in the literature focused on estimating optimal individualized treatment regimes. However, there has been less attention devoted to hypothesis testing regarding the existence of overall qualitative treatment effects, especially when there are a large number of prognosti...
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作者：Allen, Genevera I.
作者单位：Rice University
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作者：Gerstenberger, Carina; Vogel, Daniel; Wendler, Martin
作者单位：Ruhr University Bochum; University of Aberdeen; Universitat Greifswald
摘要：In many applications it is important to know whether the amount of fluctuation in a series of observations changes over time. In this article, we investigate different tests for detecting changes in the scale of mean-stationary time series. The classical approach, based on the CUSUM test applied to the squared centered observations, is very vulnerable to outliers and impractical for heavy-tailed data, which leads us to contemplate test statistics based on alternative, less outlier-sensitive sc...
