-
作者:Wang, Yixin (Iris); Ball, George; Anand, Gopesh; Park, Hyunwoo
作者单位:University of Illinois System; University of Illinois Urbana-Champaign; Indiana University System; IU Kelley School of Business; Indiana University Bloomington; Seoul National University (SNU)
摘要:Problem definition: The Food and Drug Administration (FDA) is the regulator tasked with overseeing two key dimensions of the drug supply chain: quality and shortages. Whereas the primary policy tool used by the FDA to oversee drug quality is recurring plant inspections, there are fewer similar tools used by the FDA to reduce drug shortages. In an effort to better understand the pernicious public health problem of drug shortages and the role of the FDA in reducing shortages, the U.S. Congress t...
-
作者:Baucum, Matt; Harris, Matt; Kessler, Lawrence; Luc, Guanyi
作者单位:Colorado State University System; Colorado State University Fort Collins; University of Tennessee System; University of Tennessee Knoxville; State University System of Florida; Florida State University
摘要:Problem definition: Substance use disorder (SUD) is a pressing health concern in the United States, and connecting communities with treatment is a growing public health imperative. We study the optimal allocation of substance use treatment centers across counties within U.S. states over a multiyear time horizon. We use a three-part objective function that minimizes (i) statewide overdose deaths, (ii) mismatch between counties' treatment center access and overdose death rates (inequity), and (i...
-
作者:An, Lin; Li, Andrew A.; Moseley, Benjamin; Ravi, R.
作者单位:Carnegie Mellon University
摘要:Problem definition: The classic newsvendor model yields an optimal decision for a newsvendor selecting a quantity of inventory under the assumption that the demand is drawn from a known distribution. Motivated by applications such as cloud provisioning and staffing, we consider a setting in which newsvendor-type decisions must be made sequentially in the face of demand drawn from a stochastic process that is both unknown and nonstationary. All prior work on this problem either (a) assumes that...
-
作者:Goh, You Hui; Li, Zihao; Yan, Zhenzhen
作者单位:Nanyang Technological University
摘要:Problem definition: This paper addresses an appointment scheduling problem involving multiple sequential servers using a distributionally robust optimization (DRO) approach. Two decisions are optimized: the schedule for patient visits and an adjusting policy to rebalance customers' waiting time across servers. Methodology/results: We formulate the distributionally robust appointment scheduling problem in sequential-servers systems using conic optimization, incorporating service time correlatio...
-
作者:Balseiro, Santiago R.; Lu, Haihao; Mirrokni, Vahab
作者单位:Columbia University; Alphabet Inc.; Google Incorporated; Columbia University; Massachusetts Institute of Technology (MIT); Alphabet Inc.; Google Incorporated
摘要:Problem definition: Online allocation problems with resource constraints have a rich history in operations management. In this paper, we introduce the regularized online allocation problem, a variant that includes a nonlinear regularizer acting on the total resource consumption. In this problem, requests repeatedly arrive over time, and for each request, a decision-maker needs to take an action that generates a reward and consumes resources. The objective is to simultaneously maximize additive...
-
作者:Liu, Yicheng; Chen, Xiao Alison; Liu, Yan; Wang, Zizhuo
作者单位:Shanghai University of Finance & Economics; Shanghai University of Finance & Economics; University System Of New Hampshire; University of New Hampshire; Hong Kong Polytechnic University; The Chinese University of Hong Kong, Shenzhen
摘要:Problem definition: We study a multistore assortment planning problem in which a seller centrally decides the assortment of products in each store. Each store is visited by a certain fraction of customers. Upon arrival, customers observe the products offered in the current store. The seller can either (1) show products offered in other stores to customers simultaneously (called simultaneous offering strategy) or (2) show products offered in other stores to customers if they decide not to purch...
-
作者:Chen, Huijun; Chen, Ying-Ju; Park, Sung-Hyuk; Shin, Dongwook
作者单位:Hong Kong University of Science & Technology; Hong Kong University of Science & Technology; Korea Advanced Institute of Science & Technology (KAIST)
摘要:Problem definition: This paper explores budget allocation strategies for a multichannel ad campaign, where a marketing agency strives to maximize the total conversions by dynamically adjusting budget allocation over marketing channels. A salient feature of the problem is the interplay of spillover and carryover effects; namely, customers are exposed to ads through multiple channels, and thus ads from one channel affect the effectiveness of the subsequent ads from other channels. Methodology/re...
-
作者:Federgruen, Awi; Liu, Zhe; Lu, Tiaqi
作者单位:Columbia University; Imperial College London; The Chinese University of Hong Kong, Shenzhen; The Chinese University of Hong Kong, Shenzhen
摘要:Problem definition: We study a dual sourcing problem in an increasingly volatile world. We consider two types of volatilities. External volatilities reflect fluctuating economic conditions via an underlying Markov-modulated state-of-the-world that affects the two suppliers' cost structures, capacity limits, supply mechanisms, and demands. Internal volatilities affect the actual outputs resulting from random supply processes. Demand distributions are impacted by both types of volatilities. Meth...