OPTIMAL CROSSOVER DESIGNS FOR THE COMPARISON OF 2 TREATMENTS IN THE PRESENCE OF CARRYOVER EFFECTS AND AUTO-CORRELATED ERRORS
成果类型：
Article
署名作者：
MATTHEWS, JNS
刊物名称：
BIOMETRIKA
ISSN/ISSBN：
0006-3444
DOI：
10.1093/biomet/74.2.311
发表日期：
1987
页码：
311320
关键词：
摘要：
A model for responses in a crossover experiment that includes direct and first-order carryover treatment effects, together with an autocorrelated error term, is considered when there are two treatments. A method for generating designs that minimize the variance of the estimated treatment effects is proposed and explicit results are given for the three and four period cases. Efficiencies of some practical designs are calculated.