False discovery rate control with e-values

成果类型:
Article
署名作者:
Wang, Ruodu; Ramdas, Aaditya
署名单位:
University of Waterloo; Carnegie Mellon University; Carnegie Mellon University
刊物名称:
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY
ISSN/ISSBN:
1369-7412
DOI:
10.1111/rssb.12489
发表日期:
2022
页码:
822-852
关键词:
likelihood ratio time-uniform tests
摘要:
E-values have gained attention as potential alternatives to p-values as measures of uncertainty, significance and evidence. In brief, e-values are realized by random variables with expectation at most one under the null; examples include betting scores, (point null) Bayes factors, likelihood ratios and stopped supermartingales. We design a natural analogue of the Benjamini-Hochberg (BH) procedure for false discovery rate (FDR) control that utilizes e-values, called the e-BH procedure, and compare it with the standard procedure for p-values. One of our central results is that, unlike the usual BH procedure, the e-BH procedure controls the FDR at the desired level-with no correction-for any dependence structure between the e-values. We illustrate that the new procedure is convenient in various settings of complicated dependence, structured and post-selection hypotheses, and multi-armed bandit problems. Moreover, the BH procedure is a special case of the e-BH procedure through calibration between p-values and e-values. Overall, the e-BH procedure is a novel, powerful and general tool for multiple testing under dependence, that is complementary to the BH procedure, each being an appropriate choice in different applications.