Impact of specific electromagnetic radiation on wakefulness in mice

• 成果类型: Article
• 署名作者: Deng, Hu; Liu, Lingyu; Tang, Xiaping; Lu, Yingxian; Wang, Xiaofei; Zhao, Yanyu; Shi, Yigong
• 署名单位: Tsinghua University; Tsinghua University; Peking University; Westlake Laboratory; Westlake University; Westlake University; Westlake University
• 刊物名称: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• ISSN/ISSBN: 0027-14683
• DOI: 10.1073/pnas.2313903121
• 发表日期: 2024-04-09
• 关键词: microwave-radiation; mobile phones; gsm 900; FIELDS; sleep; exposure; wcdma/umts; mechanism; wave; cw

摘要

Electromagnetic radiation (EMR) in the environment, particularly in the microwave range, may constitute a public health concern. Exposure to 2.4 GHz EMR modulated by 100 Hz square pulses was recently reported to markedly increase wakefulness in mice. Here, we demonstrate that a similar wakefulness increase can be induced by the modulation frequency of 1,000 Hz, but not 10 Hz. In contrast to the carrier frequency of 2.4 GHz, 935 MHz EMR of the same power density has little impact on wakefulness irrespective of modulation frequency. Notably, the replacement of the 100 Hz square- pulsed modulation by sinusoidal- pulsed modulation of 2.4 GHz EMR still allows a marked increase of wakefulness. In contrast, continuous sinusoidal amplitude modulation of 100 Hz with the same time- averaged power output fails to trigger any detectable change of wakefulness. Therefore, alteration of sleep behavior by EMR depends upon not just carrier frequency but also frequency and mode of the modulation. These results implicate biological sensing mechanisms for specific EMR in animals.