Symmetry engineering in 2D bioelectronics facilitating augmented biosensing interfaces

• 成果类型: Article
• 署名作者: Wu, Yizhang; Liu, Yihan; Li, Yuan; Wei, Ziquan; Xing, Sicheng; Wang, Yunlang; Zhu, Dashuai; Guo, Ziheng; Zhang, Anran; Yuan, Gongkai; Zhang, Zhibo; Huang, Ke; Wang, Yong; Wu, Guorong; Cheng, Ke; Bai, Wubin
• 署名单位: University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; North Carolina State University; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; Nanjing University; Columbia University; Michigan State University; North Carolina State University; Xidian University; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine
• 刊物名称: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• ISSN/ISSBN: 0027-13638
• DOI: 10.1073/pnas.2412684121
• 发表日期: 2024-11-26
• 关键词: performance; wireless

摘要

Symmetry lies at the heart of two- dimensional (2D) bioelectronics, determining material properties at the fundamental level. Breaking the symmetry allows emergent functionalities and effects. However, symmetry modulation in 2D bioelectronics and the resultant applications have been largely overlooked. Here, we devise an oxidized architectural MXene, referred to as oxidized MXene (OXene), that couples orbit symmetric breaking with inverse symmetric breaking to entitle the optimized interfacial impedance and Schottky- induced piezoelectric effects. The resulting OXene validates applications ranging from microelectrode arrays, gait analysis, active transistor matrix, and wireless signaling transmission, which enables high- fidelity signal transmission and reconfigurable logic gates. Furthermore, OXene interfaces were investigated in both rodent and porcine myocardium, featuring high- quality and spatiotemporally resolved physiological recordings, while accurate differentiated predictions, enabled via various machine learning pipelines.