Multifunctional biomolecular corona- inspired nanoremediation of antibiotic residues

• 成果类型: Article
• 署名作者: Hou, Jie; Lu, Yuqi; Chen, Qiqi; Liao, Xinyi; Wu, Xinyue; Sang, Kaijian; White, Jason C.; Gardea-Torresdey, Jorge L.; Xu, Jiang; Zhang, Jianying; Yang, Kun; Zhu, Lizhong; Lin, Daohui
• 署名单位: Zhejiang University; Zhejiang University; Connecticut Agricultural Experiment Station; University of Texas System; University of Texas El Paso; Zhejiang University
• 刊物名称: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• ISSN/ISSBN: 0027-12321
• DOI: 10.1073/pnas.2409955121
• 发表日期: 2024-09-03
• 关键词: iron; sweat; florfenicol; water

摘要

Facing complex and variable emerging antibiotic pollutants, the traditional development of functional materials is a trial- and- error process based on physicochemical principles, where laborious steps and long timescales make it difficult to accelerate technical breakthroughs. Notably, natural biomolecular coronas derived from highly tolerant organisms under significant contamination scenarios can be used in conjunction with nanotechnology to tackling emerging contaminants of concern. Here, super worms (Tubifex tubifex) with high pollutant tolerance were integrated with nano- zero valent iron (nZVI) to effectively reduce the content of 17 antibiotics in wastewater within 7 d. Inspired by the synergistic remediation, nZVI- augmented worms were constructed liter) alone efficiently degraded florfenicol (FF, as a representative antibiotic), while their composite removed 87% of FF (3 mu mol/L). Under antibiotic exposure, biomolecules secreted by worms formed a corona on and modified the nZVI particle surface, enabling the nano-bio interface greater functionality, including responsiveness, enrichment, and synthesize organic acids and amines as major metabolites, which were assembled into vesicles and secreted, thereby interacting with nZVI in a biologically response design highlights biomolecular coronas as a complex resource to augment nano- enabled techwith coordinated multifunctionalities.