Signatures of selection with cultural interference

• 成果类型: Article
• 署名作者: Fogarty, Laurel; Otto, Sarah P.
• 署名单位: Max Planck Society; University of British Columbia; University of British Columbia
• 刊物名称: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• ISSN/ISSBN: 0027-10414
• DOI: 10.1073/pnas.2322885121
• 发表日期: 2024-11-18
• 关键词: biological evolutionary processes; molecular population-genetics; soft sweeps; positive selection; niche construction; adaptation; transmission; coevolution; BEHAVIOR; LINKAGE

摘要

Human evolution is intricately linked with culture, which permeates almost all facets Nevertheless, our understanding of the ways in which stably transmitted, evolutionarily relevant human cultural traits might interact with the human genome is incomplete, and methods to detect such interactions are limited. Here, we describe some rules of cultural transmission which could pertain to both humans and cultural nonhuman animals that could lead to the formation and maintenance of stable associations between cultural and genetic traits. Next, we show that, in the presence of such associations, a process analogous to genetic hitchhiking is possible in gene-culture systems. These could leave signatures in the human genome similar to, and perhaps indistinguishable from, those left by selection on genetic traits. Finally, we model selective interference between cultural and genetic traits. We show that selective interference between a cultural trait under selection and a genetic trait under selection can reduce the efficacy of natural selection in the human genome, both in terms of the probability of fixation of beneficial alleles and the dynamics of selective sweeps. We then show that the efficiency of selection at genetic loci can, however, be increased in the presence of strong cultural genetic data may be complex and wide-ranging in gene-culture coevolutionary systems.