Intracortical recordings reveal the neuronal selectivity for bodies and body parts in the human visual cortex

• 成果类型: Article
• 署名作者: Ramirez, Jesus Garcia; Vanhoyland, Michael; Murty, N. A. Ratan; Decramer, Thomas; Van Paesschen, Wim; Bracci, Stefania; op de Beeck, Hans; Kanwisher, Nancy; Janssen, Peter; Theys, Tom
• 署名单位: KU Leuven; KU Leuven; KU Leuven; University Hospital Leuven; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); KU Leuven; University of Trento; KU Leuven
• 刊物名称: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• ISSN/ISSBN: 0027-10405
• DOI: 10.1073/pnas.2408871121
• 发表日期: 2024-12-09
• 关键词: stimulus representations; object shape; extrastriate; regions; responses; pathways

摘要

Body perception plays a fundamental role in social cognition. Yet, the neural mechanisms underlying this process in humans remain elusive given the spatiotemporal constraints of functional imaging. Here, we present intracortical recordings of single- and multiunit spiking activity in two epilepsy surgery patients in or near the extrastriate body area, a critical region for body perception. Our recordings revealed a strong preference for human bodies over a large range of control stimuli. Notably, body selectivity was driven by a distinct selectivity for body parts. The observed body selectivity generalized to nonphotographic depictions of bodies including silhouettes and stick figures. Overall, our study provides unique neural data that bridge the gap between human neuroimaging and macaque electrophysiology studies, laying a solid foundation for computational models of human body processing.