Pronouns reactivate conceptual representations in human hippocampal neurons
成果类型：
Article
署名作者：
Dijksterhuis, D. E.; Self, M. W.; Possel, J. K.; Peters, J. C.; van Straaten, E. C. W.; Idema, S.; Baaijen, J. C.; van der Salm, S. M. A.; Aarnoutse, E. J.; van Klink, N. C. E.; van Eijsden, P.; Hanslmayr, S.; Chelvarajah, R.; Roux, F.; Kolibius, L. D.; Sawlani, V.; Rollings, D. T.; Dehaene, S.; Roelfsema, P. R.
署名单位：
Royal Netherlands Academy of Arts & Sciences; Netherlands Institute for Neuroscience (NIN-KNAW); Maastricht University; Maastricht University; Eindhoven University of Technology; Utrecht University; Utrecht University Medical Center; University of Glasgow; University of Birmingham; University of Birmingham; Columbia University; Universite Paris Saclay; CEA; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite PSL; College de France; Vrije Universiteit Amsterdam; Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Institut National de la Sante et de la Recherche Medicale (Inserm)
刊物名称：
SCIENCE
ISSN/ISSBN：
0036-9569
DOI：
10.1126/science.adr2813
发表日期：
2024-09-27
页码：
1478-1484
关键词：
single neurons
functional neuroanatomy
working-memory
brain
perception
摘要：
During discourse comprehension, every new word adds to an evolving representation of meaning that accumulates over consecutive sentences and constrains the next words. To minimize repetition and utterance length, languages use pronouns, like the word she, to refer to nouns and phrases that were previously introduced. It has been suggested that language comprehension requires that pronouns activate the same neuronal representations as the nouns themselves. We recorded from individual neurons in the human hippocampus during a reading task. Cells that were selective to a particular noun were later reactivated by pronouns that refer to the cells' preferred noun. These results imply that concept cells contribute to a rapid and dynamic semantic memory network that is recruited during language comprehension.