Snapshots of genetic copy-and-paste machinery in action

• 成果类型: Editorial Material
• 署名作者: Cristofari, Gael
• 署名单位: Universite Cote d'Azur; Centre National de la Recherche Scientifique (CNRS); Institut National de la Sante et de la Recherche Medicale (Inserm)
• 刊物名称: Nature
• ISSN/ISSBN: 0028-5620
• DOI: 10.1038/d41586-024-00112-w
• 发表日期: 2024-02-01
• 页码: 40-42
• 关键词: reverse-transcriptase; dna; site; rna

摘要

LINE-1 DNA elements self-duplicate, inserting the copy into new regions of the genome - a key process in chromosome evolution. Structures of the machinery that performs this process in humans are now reported.