Blocking cell death limits lung damage and inflammation from influenza

• 成果类型: Editorial Material
• 署名作者: Gupta, Nishma; Silke, John
• 署名单位: Melbourne Genomics Health Alliance
• 刊物名称: Nature
• ISSN/ISSBN: 0028-6620
• DOI: 10.1038/d41586-024-00910-2
• 发表日期: 2024-04-25
• 页码: 726-727
• 关键词: oseltamivir; necroptosis; apoptosis

摘要

Animals that receive an inhibitor of an antiviral cell-death response called necroptosis are less likely to die of influenza even at a late stage of infection. This has implications for the development of therapies for respiratory diseases.