Ribosomes unexpectedly moonlight as activators of angiogenin enzyme

• 成果类型: Editorial Material
• 署名作者: Ivanov, Pavel
• 署名单位: Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Harvard Medical School
• 刊物名称: Nature
• ISSN/ISSBN: 0028-4830
• DOI: 10.1038/d41586-024-01510-w
• 发表日期: 2024-06-20
• 页码: 568-569
• 关键词: transfer-rna

摘要

The enzyme angiogenin functions in stress responses and aids the formation of blood vessels. It emerges that the ribosome takes a break from its usual role of making proteins to activate angiogenin and position it to cleave transfer RNA.