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作者:Balding, DJ; Carothers, AD; Marchini, JL; Cardon, LR; Vetta, A; Griffiths, B; Weir, BS; Hill, WG; Goldstein, D; Strimmer, K; Myers, S; Beaumont, MA; Glasbey, CA; Mayer, CD; Richardson, S; Marshall, C; Durrett, R; Nielsen, R; Visscher, PM; Knott, SA; Haley, CS; Ball, RD; Hackett, CA; Holmes, S; Husmeier, D; Jansen, RC; ter Braak, CJF; Maliepaard, CA; Boer, MP; Joyce, P; Li, N; Stephens, M; Marcoulides, GA; Drezner, Z; Mardia, K; McVean, G; Meng, XL; Ochs, MF; Pagel, M; Sha, N; Vannucci, M; Sillanpää, MJ; Sisson, S; Yandell, BS; Jin, CF; Satagopan, JM; Gaffney, PJ; Zeng, ZB; Broman, KW; Speed, TP; Fearnhead, P; Donnelly, P; Larget, B; Simon, DL; Kadane, JB; Nicholson, G; Smith, AV; Jónsson, F; Gústafsson, O; Stefánsson, K; Donnelly, P; Parmigiani, G; Garrett, ES; Anbazhagan, R; Gabrielson, E
作者单位:Imperial College London; University of Edinburgh; University of Oxford; North Carolina State University; University of Edinburgh; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; University of Munich; University of Reading; James Hutton Institute; Cornell University; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); Roslin Institute; Scion; James Hutton Institute; Stanford University; University of Groningen; University of Idaho; University of Washington; University of Washington Seattle; California State University System; California State University Fullerton; University of Leeds; University of Chicago; Fox Chase Cancer Center; Texas A&M University System; Texas A&M University College Station; University of Puerto Rico; University of Wisconsin System; University of Wisconsin Madison; North Carolina State University
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作者:Shi, JQ; Copas, J
作者单位:University of Warwick; University of Glasgow
摘要:A major difficulty in meta-analysis is publication bias. Studies with positive outcomes are more likely to be published than studies reporting negative or inconclusive results. Correcting for this bias is not possible without making untestable assumptions. In this paper, a sensitivity analysis is discussed for the meta-analysis of 2x2 tables using exact conditional distributions. A Markov chain Monte Carlo EM algorithm is used to calculate maximum likelihood estimates. A rule for increasing th...
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作者:Ollila, E; Oja, H; Hettmansperger, TP
作者单位:Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park
摘要:A new estimator of the regression parameters is introduced in a multivariate multiple-regression model in which both the vector of explanatory variables and the vector of response variables are assumed to be random. The affine equivariant estimate matrix is constructed using the sign covariance matrix (SCM) where the sign concept is based on Oja's criterion function. The influence function and asymptotic theory are developed to consider robustness and limiting efficiencies of the SCM regressio...
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作者:Lauritzen, SL; Richardson, TS
作者单位:Aalborg University; University of Washington; University of Washington Seattle
摘要:Chain graphs are a natural generalization of directed acyclic graphs and undirected graphs. However, the apparent simplicity of chain graphs belies the subtlety of the conditional independence hypotheses that they represent. There are many simple and apparently plausible, but ultimately fallacious, interpretations of chain graphs that are often invoked, implicitly or explicitly. These interpretations also lead to flawed methods for applying background knowledge to model selection. We present a...
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作者:Dawid, AP; Cox, DR; Kreiner, S; Green, P; Shipley, B; Kent, JT; Smith, JQ; Koster, JTA; Madigan, D; Andersson, SA; Perlman, MD; Robert, CP; Marin, JM; Rosenbaum, PR; Roverato, A; Consonni, G; Studeny, M
作者单位:University of London; University College London; University of Oxford; University of Copenhagen; University of Bristol; University of Sherbrooke; University of Leeds; University of Warwick; Erasmus University Rotterdam; Erasmus University Rotterdam - Excl Erasmus MC; Rutgers University System; Rutgers University New Brunswick; Indiana University System; Indiana University Bloomington; University of Washington; University of Washington Seattle; Universite PSL; Universite Paris-Dauphine; University of Pennsylvania; Universita di Modena e Reggio Emilia; University of Pavia; Czech Academy of Sciences
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作者:Efron, B
作者单位:Stanford University; Stanford University
摘要:Survival analysis problems often involve dual timescales, most commonly calendar date and lifetime, the latter being the elapsed time since an initiating event such as a heart transplant. In our main example attention is focused on the hazard rate of 'death' as a function of calendar date. Three different estimates are discussed, one each from proportional hazards analyses on the lifetime and the calendar date scales, and one from a symmetric approach called here the 'two-way proportional haza...
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作者:Barber, S; Nason, GP; Silverman, BW
作者单位:University of Bristol
摘要:We use cumulants to derive Bayesian credible intervals for wavelet regression estimates. The first four cumulants of the posterior distribution of the estimates are expressed in terms of the observed data and integer powers of the mother wavelet functions. These powers are closely approximated by linear combinations of wavelet scaling functions at an appropriate finer scale. Hence, a suitable modification of the discrete wavelet transform allows the posterior cumulants to be found efficiently ...
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作者:Wood, S; Kohn, R; Shively, T; Jiang, WX
作者单位:University of New South Wales Sydney; University of Texas System; University of Texas Austin; Northwestern University
摘要:A Bayesian approach is presented for model selection in nonparametric regression with Gaussian errors and in binary nonparametric regression. A smoothness prior is assumed for each component of the model and the posterior probabilities of the candidate models are approximated using the Bayesian information criterion. We study the model selection method by simulation and show that it has excellent frequentist properties and gives improved estimates of the regression surface. All the computation...
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作者:Larget, B; Simon, DL; Kadane, JB
作者单位:Duquesne University; Carnegie Mellon University
摘要:The determination of evolutionary relationships is a fundamental problem in evolutionary biology. Genome arrangement data are potentially more informative than deoxyribonucleic acid sequence data for inferring evolutionary relationships between distantly related taxa. We describe a Bayesian framework for phylogenetic inference from mitochondrial genome arrangement data using Markov chain Monte Carlo methods. We apply the method to assess evolutionary relationships between eight animal phyla.
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作者:Delaigle, A; Gijbels, I
作者单位:Universite Catholique Louvain
摘要:We propose a kernel estimator of integrated squared density derivatives, from a sample that has been contaminated by random noise. We derive asymptotic expressions for the bias and the variance of the estimator and show that the squared bias term dominates the variance term. This coincides with results that are available for non-contaminated observations. We then discuss the selection of the bandwidth parameter when estimating integrated squared density derivatives based on contaminated data. ...