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作者：Dunson, David B.
作者单位：National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS)
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作者：Small, Dylan S.; Ten Have, Thomas R.; Rosenbaum, Paul R.
作者单位：University of Pennsylvania; University of Pennsylvania
摘要：In the Prospect Study, in 10 pairs of two primary-care practices, one practice was picked at random to receive a depression care manager to treat its depressed patients. Randomization inference, properly performed, reflects the assignment of practices, not patients, to treatment or control. Yet, pertinent data describe individual patients: depression outcomes, baseline covariates, compliance with treatment. The methods discussed use only (i) the random assignment of clusters to treatment or co...
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作者：Cai, Zongwu; Xu, Xiaoping
作者单位：University of North Carolina; University of North Carolina Charlotte; Xiamen University; China University of Geosciences
摘要：We suggest quantile regression methods for a class of smooth coefficient time series models. We use both local polynomial and local constant litting schemes to estimate the smooth coefficients in a quantile framework. We establish the asymptotic properties of both the local polynomial and local constant estimators for alpha-mixing time series. We also suggest a bandwidth selector based on the nonparametric version of the Akaike information criterion. along with a consistent estimate of the asy...
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作者：Frees, Edward W.; Valdez, Emiliano A.
作者单位：University of Wisconsin System; University of Wisconsin Madison; University of Connecticut
摘要：This work describes statistical modeling of detailed. microlevel automobile insurance records. We consider 1993-2001 data a from it major insurance company in Singapore. By detailed microlevel records. we mean experience at the individual vehicle level, including vehicle and driver characteristics, insurance coverage, and claims experience. by year. The claims experience consists of detailed information oil the type of insurance claim such as whether the claim is due to injury to a third party...
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作者：Iaci, Ross; Yin, Xiangrong; Sriram, T. N.; Klingenberg, Christian Peter
作者单位：William & Mary; University System of Georgia; University of Georgia; University of Manchester
摘要：In this article we propose a new general index that measures relationships between multiple sets of random vectors. This index is based on Kullback-Leibler (KL) information, which measures linear or nonlinear dependence between multiple sets using joint and marginal densities of affine transformations of the random vectors. Estimates of the matrixes are obtained by maximizing the KL information and are shown to be consistent. The motivation for introducing such an index comes from morphologica...
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作者：Calder, Catherine A.; Holloman, Christopher H.; Bortnick, Steven M.; Strauss, Warren; Morara, Michele
作者单位：University System of Ohio; Ohio State University; Battelle Memorial Institute
摘要：Since the U.S. Environmental Protection Agency began widespread monitoring of PM2.5 (particulate matter <2.5 mu in diameter) concentration levels in the late 1990s, the epidemiological community has performed several observational studies directly relating PM2.5 concentration to various health endpoints including mortality and morbidity. However, recent research suggests that human exposure to the constituents of PM2.5 may differ significantly from ambient (or outdoor) PM2.5 concentration meas...
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作者：Crainiceanu, Ciprian M.; Diggle, Peter J.; Rowlingson, Barry
作者单位：Johns Hopkins University; Lancaster University; Lancaster University
摘要：We present a state-of-the-art application of smoothing for dependent bivariate binomial spatial data to Loa loa prevalence mapping in West Africa. This application starts with the nonspatial calibration of survey instruments, continues with the spatial model building and assessment, and ends with robust, tested software intended for use by field workers for online prevalence map updating. From a statistical perspective, we address several important methodological issues: building spatial model...
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作者：Sabatti, Chiara; Lange, Kenneth
作者单位：University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles
摘要：Affymetrix's SNP (single-nucleotide polymorphism) genotyping chips have increased the scope and decreased the cost of gene-mapping studies. Because each SNP is queried by multiple DNA probes, the chips present interesting challenges in genotype calling. Traditional clustering methods distinguish the three genotypes of an SNP fairly well given a large enough sample of unrelated individuals or a training sample of known genotypes. This article describes our attempt to improve genotype calling by...
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作者：Zhang, Heping; Ye, Yuanqing; Diggle, Peter; Shi, Jian
作者单位：Yale University; Jiangxi Normal University; Lancaster University; Johns Hopkins University; Chinese Academy of Sciences; Academy of Mathematics & System Sciences, CAS
摘要：Exposure to ambient pollutants at concentrations above defined standards is a risk factor for respiratory symptoms, especially in sensitive children. Many studies have been undertaken to monitor air quality and to assess its association with respiratory symptoms. We propose a joint mixed-effects regression model of time series measures and recurrent events to analyze the air quality and respiratory symptom data from the Yale Mothers and Infants Health Study. Three mothers' symptoms (runny nose...
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作者：Hill, Jennifer
作者单位：New York University
