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作者:Wei, Ying; Carroll, Raymond J.
作者单位:Columbia University; Texas A&M University System; Texas A&M University College Station
摘要:Regression quantiles can be substantially biased when the covariates are measured with error. In this paper we propose a new method that produces consistent linear quantile estimation in the presence of covariate measurement error. The method corrects the measurement error induced bias by constructing joint estimating equations that simultaneously hold for all the quantile levels. An iterative EM-type estimation algorithm to obtain the Solutions to Such joint estimation equations is provided. ...
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作者:O'Sullivan, Finbarr; Muzi, Mark; Spence, Alexander M.; Mankoff, David M.; O'Sullivan, Janet N.; Fitzgerald, Niall; Newman, George C.; Krohn, Kenneth A.
作者单位:University College Cork; University of Washington; University of Washington Seattle; Yeshiva University
摘要:Kinetic analysis is used to extract metabolic information from dynamic positron emission tomography (PET) uptake data. The theory of indicator dilutions, developed in the seminal work of Meier and Zierler (1954), provides a probabilistic framework for representation of PET tracer uptake data in terms of a convolution between an arterial input function and a tissue residue. The residue is a scaled Survival function associated with tracer residence in the tissue. Nonparametric inference for the ...
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作者:Fearnhead, Paul; Vasileiou, Despina
作者单位:Lancaster University
摘要:Statistical identification of isochore structure, the variation in large-scale GC composition (proportion of DNA bases that are G or C as opposed to A or T), of mammalian genomes is a necessary requirement for understanding both the evolution of base composition and the many genomic features such as mutation and recombination rates, which covary with base composition. We have developed a Bayesian method for isochore analysis that we demonstrate to be more accurate than the commonly used binary...
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作者:Carroll, Raymond J.; Delaigle, Aurore; Hall, Peter
作者单位:Texas A&M University System; Texas A&M University College Station; University of Bristol; University of Melbourne; University of California System; University of California Davis
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作者:Einmahl, John H. J.; Li, Jun; Liu, Regina Y.
作者单位:Tilburg University; Tilburg University; University of California System; University of California Riverside; Rutgers University System; Rutgers University New Brunswick
摘要:This article develops a threshold system for monitoring airline performance. This threshold system divides the sample space into regions with increasing levels of risk and allows instant assessments of risk level of any observed airline performance. Of particular concern is the performance with extreme risk. In this article. a multivariate extreme value theory approach is used to establish thresholds for signaling varying levels of extremeness in the context of simultaneous monitoring of multi...
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作者:Schaubel, Douglas E.; Wolfe, Robert A.; Sima, Camelia S.; Merion, Robert M.
作者单位:University of Michigan System; University of Michigan; Arbor Research Collaborative for Health; Memorial Sloan Kettering Cancer Center; University of Michigan System; University of Michigan
摘要:Few health policy issues in the U.S. are scrutinized as intensely as the distribution of organs for transplantation, with much effort currently underway to examine the efficacy of existing organ allocation algorithms. The design of efficient organ a I location policies depends strongly upon accurate estimates of the Survival benefit of transplantation. Many organ allocation policies order patients on the wait-list based on time-dependent health status measures (internal time-dependent covariat...
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作者:Chib, Siddhartha; Ergashev, Bakhodir
作者单位:Washington University (WUSTL); Federal Reserve System - USA; Federal Reserve Bank - Richmond
摘要:In finance and economics much work has been done on the theoretical modeling and statistical estimation of the yield curve, defined as the relationship between -1/tau logp(t)(tau) and tau, where p(t)(tau) is the time t price of a zero-coupon bond with payoff I at maturity date t + tau. Of considerable current interest are models of the yield curve in which a collection of observed and latent factors determine the market price of factor risks, the stochastic discount factor, and the arbitrage-f...
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作者:El Ghouch, Anouar; Genton, Marc G.
作者单位:University of Geneva; Texas A&M University System; Texas A&M University College Station
摘要:We propose a new approach to conditional quantile function estimation that combines both parametric and nonparametric techniques. At each design point, a global, possibly incorrect, pilot parametric model is locally adjusted through a kernel smoothing fit. The resulting quantile regression estimator behaves like a parametric estimator when the latter is correct and converges to the nonparametric solution as the parametric start deviates from the true underlying model. We give a Bahadur-type re...
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作者:Fokianos, Konstantinos; Rahbek, Anders; Tjostheim, Dag
作者单位:University of Cyprus; University of Copenhagen; CREATES; University of Bergen
摘要:In this article we consider geometric ergodicity and likelihood-based inference for linear and nonlinear Poisson autoregression. In the linear case, the conditional mean is linked linearly to its past values, as well as to the observed values of the Poisson process. This also applies to the conditional variance, making possible interpretation as an integer-valued generalized autoregressive conditional heteroscedasticity process. In a nonlinear conditional Poisson model, the conditional mean is...
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作者:Love, Tanzy; Carriquiry, Alicia
作者单位:Iowa State University; Pontificia Universidad Catolica de Chile
摘要:We analyze data collected in a somatic embryogenesis experiment carried out on Zea mays at Iowa state university. The main objective of the Study was to identify the set of genes in maize that actively participate in embryo development. Embryo tissue was sampled and analyzed at various time periods and under different mediums and light conditions. As is the case in many microarray experiments. the operator scanned each Slide multiple times to find the slide-specific 'optimal' laser and sensor ...