作者：Feinberg, Andrew P.; Levchenko, Andre
作者单位：Johns Hopkins University; Johns Hopkins University; Johns Hopkins University; Yale University; Yale University
摘要：The concept of an epigenetic landscape describing potential cellular fates arising from pluripotent cells, first advanced by Conrad Waddington, has evolved in light of experiments showing nondeterministic outcomes of regulatory processes and mathematical methods for quantifying stochasticity. In this Review, we discuss modern approaches to epigenetic and gene regulation landscapes and the associated ideas of entropy and attractor states, illustrating how their definitions are both more precise...
作者：Liang, Mei; Chen, Wenjie; LaFountain, Amy M.; Liu, Yuanlong; Peng, Foen; Xia, Rui; Bradshaw, H. D.; Yuan, Yao-Wu
作者单位：University of Connecticut; Chinese Academy of Sciences; Chinese Academy of Sciences; South China Agricultural University; University of Washington; University of Washington Seattle; Haverford College; University of Connecticut
摘要：Taxon-specific small RNA loci are widespread in eukaryotic genomes, yet their role in lineage-specific adaptation, phenotypic diversification, and speciation is poorly understood. Here, we report that a speciation locus in monkeyflowers (Mimulus), YELLOW UPPER (YUP), contains an inverted repeat region that produces small interfering RNAs (siRNAs) in a phased pattern. Although the inverted repeat is derived from a partial duplication of a protein-coding gene that is not involved in flower pigme...
作者：Parey, Elise; Louis, Alexandra; Montfort, Jerome; Bouchez, Olivier; Roques, Celine; Iampietro, Carole; Lluch, Jerome; Castinel, Adrien; Donnadieu, Cecile; Desvignes, Thomas; Bucao, Christabel Floi; Jouanno, Elodie; Wen, Ming; Mejri, Sahar; Dirks, Ron; Jansen, Hans; Henkel, Christiaan; Chen, Wei-Jen; Zahm, Margot; Cabau, Cedric; Klopp, Christophe; Thompson, Andrew; Robinson-Rechavi, Marc; Braasch, Ingo; Lecointre, Guillaume; Bobe, Julien; Postlethwait, John H.; Berthelot, Camille; Crollius, Hugues Roest; Guiguen, Yann
作者单位：Institut National de la Sante et de la Recherche Medicale (Inserm); Universite PSL; Ecole Normale Superieure (ENS); Centre National de la Recherche Scientifique (CNRS); INRAE; INRAE; University of Oregon; University of Lausanne; Swiss Institute of Bioinformatics; Hunan Normal University; State University System of Florida; Florida Atlantic University; Harbor Branch Oceanographic Institute Foundation; Leiden University; Leiden University - Excl LUMC; Norwegian University of Life Sciences; National Taiwan University; Universite de Toulouse; Ecole Nationale Veterinaire de Toulouse; INRAE; INRAE; Michigan State University; Michigan State University; Universite PSL; Ecole Pratique des Hautes Etudes (EPHE); Centre National de la Recherche Scientifique (CNRS); Museum National d'Histoire Naturelle (MNHN); Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Institut National de la Sante et de la Recherche Medicale (Inserm); Pasteur Network; Universite Paris Cite; Institut Pasteur Paris; University of London; University College London
摘要：Accurate species phylogenies are a prerequisite for all evolutionary research. Teleosts are the largest and most diversified group of extant vertebrates, but relationships among their three oldest extant lineages remain unresolved. On the basis of seven high-quality new genome assemblies in Elopomorpha (tarpons, eels), we revisited the topology of the deepest branches of the teleost phylogeny using independent gene sequence and chromosomal rearrangement phylogenomic approaches. These analyses ...
作者：Buckley, Ralf
作者单位：Griffith University; Griffith University - Gold Coast Campus
作者：Monniaux, Marie
作者单位：INRAE; Centre National de la Recherche Scientifique (CNRS); Ecole Normale Superieure de Lyon (ENS de LYON); Universite Claude Bernard Lyon 1
