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作者：Ruan, Lin-Xin; Sun, Bo; Liu, Jia-Ming; Shi, Shi-Liang
作者单位：Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Shanghai Institute of Organic Chemistry, CAS
摘要：Despite the importance of enantioenriched alcohols in medicinal chemistry, total synthesis, and materials science, the efficient and selective construction of enantioenriched tertiary alcohols bearing two contiguous stereocenters has remained a substantial challenge. We report a platform for their preparation through the enantioconvergent, nickel-catalyzed addition of organoboronates to racemic, nonactivated ketones. We prepared several important classes of a,b-chiral tertiary alcohols in a si...
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作者：Ebrahim, Shimaa A. M.; Dweck, Hany K. M.; Weiss, Brian L.; Carlson, John R.
作者单位：Yale University; Yale University
摘要：Tsetse flies transmit trypanosomes-parasites that cause devastating diseases in humans and livestock-across much of sub-Saharan Africa. Chemical communication through volatile pheromones is common among insects; however, it remains unknown if and how such chemical communication occurs in tsetse flies. We identified methyl palmitoleate (MPO), methyl oleate, and methyl palmitate as compounds that are produced by the tsetse fly Glossina morsitans and elicit strong behavioral responses. MPO evoked...
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作者：Clery, Daniel
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作者：Hess, Evan M.; Gould, Todd D.
作者单位：University System of Maryland; University of Maryland Baltimore; University System of Maryland; University of Maryland Baltimore; University System of Maryland; University of Maryland Baltimore
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作者：Schmit, C. D.; Doerr, M. J.; Wagner, J. K.
作者单位：Texas A&M University System; Texas A&M University College Station; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park
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作者：Lin, Jianwei; Wu, Yiping; Tian, Gaofei; Yu, Daqi; Yang, Eunjeong; Lam, Wai Hei; Liu, Zheng; Jing, Yihang; Dang, Shangyu; Bao, Xiucong; Wong, Jason Wing Hon; Zhai, Yuanliang; Li, Xiang David
作者单位：University of Hong Kong; Hong Kong University of Science & Technology; Shenzhen Bay Laboratory; University of Hong Kong; University of Hong Kong
摘要：Methylation of histone H3 lysine-79 (H3K79) is an epigenetic mark for gene regulation in development, cellular differentiation, and disease progression. However, how this histone mark is translated into downstream effects remains poorly understood owing to a lack of knowledge about its readers. We developed a nucleosome-based photoaffinity probe to capture proteins that recognize H3K79 dimethylation (H3K79me2) in a nucleosomal context. In combination with a quantitative proteomics approach, th...
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作者：Hou, Sukuan; Shi, Qinqin; Benton, Michael J.; Solounias, Nikos
作者单位：Chinese Academy of Sciences; Institute of Vertebrate Paleontology & Paleoanthropology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; University of Bristol; New York Institute Technology; American Museum of Natural History (AMNH)
摘要：Wang et al. (Research Articles, 3 June 2022, eabl8316) reported an early Miocene giraffoid that exhibited fierce head-butting behavior and concluded that sexual selection promoted head-neck evolution in giraffoids. However, we argue that this ruminant is not a giraffoid and thus that the hypothesis that sexual selection promoted giraffoid head-neck evolution is not sufficiently supported.
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作者：Shreedharan, Srisharan; Saffer, Demian; Wallace, Laura M.; Williams, Charles
作者单位：University of Texas System; University of Texas Austin; Utah System of Higher Education; Utah State University; University of Texas System; University of Texas Austin; GNS Science - New Zealand
摘要：Plate motion on shallow subduction megathrusts is accommodated by a spectrum of tectonic slip modes. However, the frictional properties and conditions that sustain these diverse slip behaviors remain enigmatic. Frictional healing is one such property, which describes the degree of fault restrengthening between earthquakes. We show that the frictional healing rate of materials entrained along the megathrust at the northern Hikurangi margin, which hosts well-characterized recurring shallow slow ...
