6650期

最新文章

• The increasing effects of light pollution on professional and amateur astronomy AI翻译
  作者：Perez, Antonia M. Varela
  作者单位：Instituto de Astrofisica de Canarias
  摘要：The starry sky has been a source of inspiration throughout human history. Astronomy has been a common element in all cultures and civilizations, being used to establish calendars, navigate and discover new lands, and drive numerous scientific and technical breakthroughs. This Review discusses how it is becoming increasingly difficult for professional and amateur astronomers to observe the night sky because of light pollution. Artificial light at night, radio interference, and the deployment of...
• Modification of ground-state chemical reactivity via light-matter coherence in infrared cavities AI翻译
  作者：Ahn, Wonmi; Triana, Johan F.; Recabal, Felipe; Herrera, Felipe; Simpkins, Blake S.
  作者单位：Ihsan Dogramaci Bilkent University; Universidad de Santiago de Chile; United States Department of Defense; United States Navy; United States Naval Research Laboratory
  摘要：Reaction-rate modifications for chemical processes due to strong coupling between reactant molecular vibrations and the cavity vacuum have been reported; however, no currently accepted mechanisms explain these observations. In this work, reaction-rate constants were extracted from evolving cavity transmission spectra, revealing resonant suppression of the intracavity reaction rate for alcoholysis of phenyl isocyanate with cyclohexanol. We observed up to an 80% suppression of the rate by tuning...
• DOE lab would probe climate effects on poor communities New national lab would go to a historically Black institution AI翻译
  作者：Mervis, Jeffrey
• Protect fragile mountaintop ecosystems AI翻译
  作者：Shen, Shi-Kang; Zhou, Xiong-Li; Wang, Si-Qi; Lyu, Zhenyu; Zhang, Rui; Yang, Liu; Long, Bo
  作者单位：Yunnan University
• Leaves and sporangia developed in rare non-Fibonacci spirals in early leafy plants AI翻译
  作者：Turner, Holly-Anne; Humpage, Matthew; Kerp, Hans; Hetherington, Alexander J.
  作者单位：University of Edinburgh; University of Munster; University College Cork
  摘要：Lateral plant organs, including leaves and reproductive structures, are arranged on stems in distinct patterns termed phyllotaxis. Most extant plants exhibit phyllotactic patterns that are mathematically described by the Fibonacci series. However, it remains unclear what lateral organ arrangements were present in early leafy plants. To investigate this, we quantified phyllotaxis in fossils of the Early Devonian lycopod Asteroxylon mackiei. We report diverse phyllotaxis in leaves, including who...
• Antacid for the ocean AI翻译
  作者：Brainard, Jeffrey
• Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution AI翻译
  作者：Lu, Tzu-Chiao; Brbic, Maria; Park, Ye-Jin; Jackson, Tyler; Chen, Jiaye; Kolluru, Sai Saroja; Qi, Yanyan; Katheder, Nadja Sandra; Cai, Xiaoyu Tracy; Lee, Seungjae; Chen, Yen -Chung; Auld, Niccole; Liang, Chung-Yi; Ding, Sophia H.; Welsch, Doug; D'Souza, Samuel; Pisco, Angela Oliveira; Jones, Robert C.; Leskovec, Jure; Lai, Eric C.; Bellen, Hugo J.; Luo, Liqun; Jasper, Heinrich; Quake, Stephen R.; Li, Hongjie
  作者单位：Baylor College of Medicine; Baylor College of Medicine; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Baylor College of Medicine; Baylor College of Medicine; Baylor College Medical Hospital; Baylor College of Medicine; Baylor College of Medicine; Stanford University; Stanford University; Chan Zuckerberg Initiative (CZI); Roche Holding; Roche Holding USA; Genentech; Memorial Sloan Kettering Cancer Center; New York University; Stanford University; Stanford University; Howard Hughes Medical Institute
  摘要：Aging is characterized by a decline in tissue function, but the underlying changes at cellular resolution across the organism remain unclear. Here, we present the Aging Fly Cell Atlas, a single-nucleus transcriptomic map of the whole aging Drosophila. We characterized 163 distinct cell types and performed an in-depth analysis of changes in tissue cell composition, gene expression, and cell identities. We further developed aging clock models to predict fly age and show that ribosomal gene expre...
• After Ukrainian dam breach, war hampers study of ecological toll Mines and active combat make fieldwork too risky AI翻译
  作者：Stokstad, Erik
• How the molecules of life became one-handed Breakthrough experiments suggest magnetic materials skewed early biomolecules AI翻译
  作者：Service, Robert F.
• An enzyme cascade enables production of therapeutic oligonucleotides in a single operation AI翻译
  作者：Moody, E. R.; Obexer, R.; Nickl, F.; Spiess, R.; Lovelock, S. L.
  作者单位：University of Manchester
  摘要：Therapeutic oligonucleotides have emerged as a powerful drug modality with the potential to treat a wide range of diseases; however, the rising number of therapies poses a manufacturing challenge. Existing synthetic methods use stepwise extension of sequences immobilized on solid supports and are limited by their scalability and sustainability. We report a biocatalytic approach to efficiently produce oligonucleotides in a single operation where polymerases and endonucleases work in synergy to ...