6653期

最新文章

• After race ban, other routes to diversity beckon AI翻译
  作者：Mervis, Jeffrey
• Tandems have the power Perovskite-silicon tandem solar cells b reak the 30% efficiency threshold AI翻译
  作者：De Wolf, Stefaan; Aydin, Erkan
  作者单位：King Abdullah University of Science & Technology
  摘要：One way to increase the efficiency of a solar cell is to optimize it to the wide spectrum of sunlight for conversion into electricity. In this vein, a tandem solar cell may comprise a top cell that absorbs high-energy photons and a bottom cell that absorbs low-energy photons. Such a device can be fabricated as a stack of layers, with the top and bottom cell interconnected to each other. Monolithic integration of a perovskite solar cell and silicon solar cell into a tandem device is a promising...
• Winning a Nobel Prize may be bad for your productivity AI翻译
  作者：Shultz, David
• Translation dynamics in human cells visualized at high resolution reveal cancer drug action AI翻译
  作者：Xing, Huaipeng; Taniguchi, Reiya; Khusainov, Iskander; Kreysing, Jan Philipp; Welsch, Sonja; Turonova, Beata; Beck, Martin
  作者单位：Max Planck Society; Goethe University Frankfurt; Max Planck Society; Goethe University Frankfurt
  摘要：Ribosomes catalyze protein synthesis by cycling through various functional states. These states have been extensively characterized in vitro, but their distribution in actively translating human cells remains elusive. We used a cryo-electron tomography-based approach and resolved ribosome structures inside human cells with high resolution. These structures revealed the distribution of functional states of the elongation cycle, a Z transfer RNA binding site, and the dynamics of ribosome expansi...
• Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing AI翻译
  作者：Liu, Shiheng; Wang, Hong; Li, Xiaorun; Zhang, Fan; Lee, Jane K. J.; Li, Zihang; Yu, Clinton; Hu, Jason J.; Zhao, Xiaojing; Suematsu, Takuma; Alvarez-Cabrera, Ana L.; Liu, Qiushi; Zhang, Liye; Huang, Lan; Aphasizheva, Inna; Aphasizhev, Ruslan; Zhou, Z. Hong
  作者单位：University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; Boston University; ShanghaiTech University; University of California System; University of California Irvine; Boston University
  摘要：In Trypanosoma brucei, the editosome, composed of RNA-editing substrate-binding complex (RESC) and RNA-editing catalytic complex (RECC), orchestrates guide RNA (gRNA)-programmed editing to recode cryptic mitochondrial transcripts into messenger RNAs (mRNAs). The mechanism of information transfer from gRNA to mRNA is unclear owing to a lack of high-resolution structures for these complexes. With cryo-electron microscopy and functional studies, we have captured gRNA-stabilizing RESC-A and gRNA-m...
• Succinct discoveries that inspire AI翻译
  作者：[Anonymous]
• Principles of human pre-60S biogenesis AI翻译
  作者：Broeck, Arnaud Vanden; Klinge, Sebastian
  作者单位：Rockefeller University
  摘要：INTRODUCTIONRibosomes, two-subunit RNA-protein nanomachines, translate messenger RNA (mRNA) into proteins in all living organisms. The small ribosomal subunit (40S) is responsible for decoding of mRNA, whereas the large subunit (60S) catalyzes peptide bond formation. Assembly of both ribosomal subunits in human cells is initiated in the nucleolus, followed by nuclear and cytoplasmic maturation, and requires more than 200 ribosome assembly factors catalyzing modification, processing, and foldin...
• The future of bears AI翻译
  作者：Can, Ozgun Emre
  作者单位：Ankara University
• The star watcher AI翻译
  作者：Normile, Dennis
• An expanded view of transcription AI翻译
  作者：Stasevich, Timothy J.; Kimura, Hiroshi
  作者单位：Colorado State University System; Colorado State University Fort Collins; Institute of Science Tokyo; Tokyo Institute of Technology