6661期

最新文章

• The raw material of evolution AI翻译
  作者：Hoelzel, A. Rus; Lynch, Michael
  作者单位：Durham University; Arizona State University; Arizona State University-Tempe
• Tensions endanger US-China research agreement AI翻译
  作者：Mervis, Jeffrey
• Green decommissioning for renewables in China AI翻译
  作者：Xia, Siyou; Yang, Yu; Liu, Yi; Poon, Jessie
  作者单位：Chinese Academy of Sciences; Institute of Geographic Sciences & Natural Resources Research, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; State University of New York (SUNY) System; University at Buffalo, SUNY
• Intracellular tPA-PAI-1 interaction determines VLDL assembly in hepatocytes AI翻译
  作者：Dai, Wen; Zhang, Heng; Lund, Hayley; Zhang, Ziyu; Castleberry, Mark; Rodriguez, Maya; Kuriakose, George; Gupta, Sweta; Lewandowska, Magdalena; Powers, Hayley R.; Valmiki, Swati; Zhu, Jieqing; Shapiro, Amy D.; Hussain, M. Mahmood; Lopez, Jose A.; Sorci-Thomas, Mary G.; Silverstein, Roy L.; Ginsberg, Henry N.; Sahoo, Daisy; Tabas, Ira; Zheng, Ze
  作者单位：Medical College of Wisconsin; Marquette University; NewYork-Presbyterian Hospital; Columbia University; Indiana Hemophilia & Thrombosis Center; Medical College of Wisconsin; State University of New York (SUNY) System; SUNY Downstate Health Sciences University; University of Washington; University of Washington Seattle; Medical College of Wisconsin; Medical College of Wisconsin; Columbia University; NewYork-Presbyterian Hospital; Columbia University; NewYork-Presbyterian Hospital; Columbia University; Medical College of Wisconsin
  摘要：INTRODUCTION: Tissue plasminogen activator (tPA) is a serine protease that initiates fibrinolysis to remove excessive blood clots and restore blood flow. Intravenous infusion of recombinant tPA is approved as a thrombolytic therapy in thrombotic cardiovascular diseases, including ischemic stroke and myocardial infarction. Low plasma tPA activity is associated with a higher risk of atherosclerotic cardiovascular disease and atherogenic apolipoprotein B (apoB)-lipoprotein cholesterol levels in h...
• Stephen Brown with Mark Rylance AI翻译
  作者：Firestein, Stuart
  作者单位：Columbia University; The Santa Fe Institute
• Why do cats love tuna so much? AI翻译
  作者：Grimm, David
• Genomic inference of a severe human bottleneck during the Early to Middle Pleistocene transition AI翻译
  作者：Hu, Wangjie; Hao, Ziqian; Du, Pengyuan; Di Vincenzo, Fabio; Manzi, Giorgio; Cui, Jialong; Fu, Yun-Xin; Pan, Yi-Hsuan; Li, Haipeng
  作者单位：Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Shanghai Institute of Nutrition & Health, CAS; East China Normal University; Shandong First Medical University & Shandong Academy of Medical Sciences; University of Florence; Sapienza University Rome; University of Texas System; University of Texas Health Science Center Houston; University of Texas School Public Health; Yunnan University; Chinese Academy of Sciences
  摘要：Population size history is essential for studying human evolution. However, ancient population size history during the Pleistocene is notoriously difficult to unravel. In this study, we developed a fast infinitesimal time coalescent process (FitCoal) to circumvent this difficulty and calculated the composite likelihood for present-day human genomic sequences of 3154 individuals. Results showed that human ancestors went through a severe population bottleneck with about 1280 breeding individuals...
• The climate crisis is a crisis of inequality AI翻译
  作者：Pande, Rohini
  作者单位：Yale University
• Wild pedigrees inform mutation rates and historic abundance in baleen whales AI翻译
  作者：Suarez-Menendez, Marcos; Berube, Martine; Furni, Fabricio; Rivera-Leon, Vania E.; Heide-Jorgensen, Mads-Peter; Larsen, Finn; Sears, Richard; Ramp, Christian; Eriksson, Britas Klemens; Etienne, Rampal S.; Robbins, Jooke; Palsboll, Per J.
  作者单位：University of Groningen; Greenland Institute of Natural Resources; University of St Andrews
  摘要：Phylogeny-based estimates suggesting a low germline mutation rate (mu) in baleen whales have influenced research ranging from assessments of whaling impacts to evolutionary cancer biology. We estimated mu directly from pedigrees in four baleen whale species for both the mitochondrial control region and nuclear genome. The results suggest values higher than those obtained through phylogeny-based estimates and similar to pedigree-based values for primates and toothed whales. Applying our estimat...
• Strengthen management of offshore aquaculture AI翻译
  作者：Peng, Daomin; Zhu, Yugui; Chu, Jiansong
  作者单位：Ocean University of China; University of British Columbia; Ocean University of China; Southern Marine Science & Engineering Guangdong Laboratory; Southern Marine Science & Engineering Guangdong Laboratory (Guangzhou)