作者：Martinez-Sanchez, Noelia; Ray, David
作者单位：University of Oxford; University of Oxford; University of Oxford
作者：Woodie, Lauren N.; Melink, Lily C.; Midha, Mohit; de Araujo, Alan M.; Geisler, Caroline E.; Alberto, Ahren J.; Krusen, Brianna M.; Zundell, Delaine M.; de Lartigue, Guillaume; Hayes, Matthew R.; Lazar, Mitchell A.
作者单位：University of Pennsylvania; University of Pennsylvania; Monell Chemical Senses Center; University of Pennsylvania; University of Pennsylvania
摘要：Circadian desynchrony induced by shiftwork or jet lag is detrimental to metabolic health, but how synchronous or desynchronous signals are transmitted among tissues is unknown. We report that liver molecular clock dysfunction is signaled to the brain through the hepatic vagal afferent nerve (HVAN), leading to altered food intake patterns that are corrected by ablation of the HVAN. Hepatic branch vagotomy also prevents food intake disruptions induced by high-fat diet feeding and reduces body we...
作者：Zhao, T. Christina
作者单位：University of Washington; University of Washington Seattle
作者：Tian, Zhen; Song, Jiachen; Zhao, Xuying; Zhou, Yiming; Chen, Xi; Le, Qiumin; Wang, Feifei; Ma, Lan; Liu, Xing
作者单位：Fudan University
摘要：The structurally symmetric mammalian brain hemispheres are interconnected by commissural axons across the midline. However, the functions of interhemispheric connectivity remain largely unknown. We found that in mice, transection of the anterior commissure (AC), which connects the rostroventral forebrain, impaired avoidant behaviors. The basolateral amygdala (BLA) in the mouse projects to the contralateral nucleus accumbens (NAc) through the AC, independent of its ipsilateral projections. Aver...
作者：Capua, Ilaria; Fanelli, Angela
作者单位：Johns Hopkins University; European Commission Joint Research Centre; EC JRC ISPRA Site
