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作者：Wei, Chao; Jiang, Wei; Wang, Ruiyu; Zhong, Haoyu; He, Huabin; Gao, Xinwei; Zhong, Shilin; Yu, Fengting; Guo, Qingchun; Zhang, Li; Schiffelers, Lisa D. J.; Zhou, Bin; Trepel, Martin; Schmidt, Florian I.; Luo, Minmin; Shao, Feng
作者单位：Chinese Institute for Brain Research, Beijing; National Institute of Biological Sciences, Beijing; Chinese Academy of Medical Sciences - Peking Union Medical College; University of Bonn; Chinese Academy of Sciences; Center for Excellence in Molecular Cell Science, CAS; Chinese Academy of Medical Sciences - Peking Union Medical College; Tsinghua University; Changping Laboratory
摘要：The blood-brain barrier (BBB) protects the central nervous system from infections or harmful substances(1); its impairment can lead to or exacerbate various diseases of the central nervous system(2-4). However, the mechanisms of BBB disruption during infection and inflammatory conditions(5,6) remain poorly defined. Here we find that activation of the pore-forming protein GSDMD by the cytosolic lipopolysaccharide (LPS) sensor caspase-11 (refs. (7-9)), but not by TLR4-induced cytokines, mediates...
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作者：Stiller, Josefin; Feng, Shaohong; Chowdhury, Al-Aabid; Rivas-Gonzalez, Iker; Duchene, David A.; Fang, Qi; Deng, Yuan; Kozlov, Alexey; Stamatakis, Alexandros; Claramunt, Santiago; Nguyen, Jacqueline M. T.; Ho, Simon Y. W.; Faircloth, Brant C.; Haag, Julia; Houde, Peter; Cracraft, Joel; Balaban, Metin; Mai, Uyen; Chen, Guangji; Gao, Rongsheng; Zhou, Chengran; Xie, Yulong; Huang, Zijian; Cao, Zhen; Yan, Zhi; Ogilvie, Huw A.; Nakhleh, Luay; Lindow, Bent; Morel, Benoit; Fjeldsa, Jon; Hosner, Peter A.; da Fonseca, Rute R.; Petersen, Bent; Tobias, Joseph A.; Szekely, Tamas; Kennedy, Jonathan David; Reeve, Andrew Hart; Liker, Andras; Stervander, Martin; Antunes, Agostinho; Tietze, Dieter Thomas; Bertelsen, Mads F.; Lei, Fumin; Rahbek, Carsten; Graves, Gary R.; Schierup, Mikkel H.; Warnow, Tandy; Braun, Edward L.; Gilbert, M. Thomas P.; Jarvis, Erich D.; Mirarab, Siavash; Zhang, Guojie
作者单位：University of Copenhagen; Zhejiang University; Zhejiang University; Zhejiang University; University of Sydney; Aarhus University; University of Copenhagen; Beijing Genomics Institute (BGI); Heidelberg Institute for Theoretical Studies; Foundation for Research & Technology - Hellas (FORTH); Helmholtz Association; Karlsruhe Institute of Technology; University of Toronto; Royal Ontario Museum; Flinders University South Australia; Australian Museum; Louisiana State University System; Louisiana State University; Louisiana State University System; Louisiana State University; New Mexico State University; American Museum of Natural History (AMNH); University of California System; University of California San Diego; University of California System; University of California San Diego; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Rice University; University of Copenhagen; University of Copenhagen; AIMST University; Imperial College London; University of Bath; University of Debrecen; HUN-REN; Office for Supported Research Groups (ELKH); University of Copenhagen; University of Pannonia; University of Pannonia; Natural History Museum London; Universidade do Porto; Universidade do Porto; Chinese Academy of Sciences; Institute of Zoology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Peking University; University of Southern Denmark; Smithsonian Institution; Smithsonian National Museum of Natural History; University of Illinois System; University of Illinois Urbana-Champaign; State University System of Florida; University of Florida; Norwegian University of Science & Technology (NTNU); Rockefeller University; Howard Hughes Medical Institute; University of California System; University of California San Diego; University of Copenhagen
摘要：Despite tremendous efforts in the past decades, relationships among main avian lineages remain heavily debated without a clear resolution. Discrepancies have been attributed to diversity of species sampled, phylogenetic method and the choice of genomic regions(1-3). Here we address these issues by analysing the genomes of 363bird species(4) (218taxonomic families, 92% of total). Using intergenic regions and coalescent methods, we present a well-supported tree but also a marked degree of discor...
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作者：Elson, Malte
作者单位：University of Bern
摘要：Borrowing the idea of 'bug bounties' from the technology industry could provide a systematic way to detect and correct the errors that litter the scientific literature.
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作者：Castelvecchi, Davide
摘要：Experiments generate quantum entanglement over optical fibres across three real cities, marking progress towards networks that could have revolutionary applications.
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作者：Wang, Chengli; Li, Zihan; Riemensberger, Johann; Lihachev, Grigory; Churaev, Mikhail; Kao, Wil; Ji, Xinru; Zhang, Junyin; Blesin, Terence; Davydova, Alisa; Chen, Yang; Huang, Kai; Wang, Xi; Ou, Xin; Kippenberg, Tobias J.
作者单位：Chinese Academy of Sciences; Shanghai Institute of Microsystem & Information Technology, CAS; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
摘要：Electro-optical photonic integrated circuits (PICs) based on lithium niobate (LiNbO3) have demonstrated the vast capabilities of materials with a high Pockels coefficient(1,2). They enable linear and high-speed modulators operating at complementary metal-oxide-semiconductor voltage levels(3) to be used in applications including data-centre communications(4), high-performance computing and photonic accelerators for AI(5). However, industrial use of this technology is hindered by the high cost p...
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作者：Zweibel, Ellen
作者单位：University of Wisconsin System; University of Wisconsin Madison
摘要：A phenomenon that affects the magnetic fields of rotating bodies could be involved in recurring changes in the Sun's behaviour, which are related to a periodic flipping of its field. The proposal is a fresh take on this strange effect.
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作者：Ewbank, Jonathan
摘要：Letter to the Editor
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作者：Wong, Carissa
摘要：Google scientists have modelled a fragment of the human brain at nanoscale resolution, revealing cells with previously undiscovered features.
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作者：Wienhausen, Gerrit; Moraru, Cristina; Bruns, Stefan; Tran, Den Quoc; Sultana, Sabiha; Wilkes, Heinz; Dlugosch, Leon; Azam, Farooq; Simon, Meinhard
作者单位：Carl von Ossietzky Universitat Oldenburg; University of California System; University of California San Diego; Scripps Institution of Oceanography; University of Duisburg Essen
摘要：Cobalamin (vitamin B-12, herein referred to as B-12) is an essential cofactor for most marine prokaryotes and eukaryotes(1,2). Synthesized by a limited number of prokaryotes, its scarcity affects microbial interactions and community dynamics(2-4). Here we show that two bacterial B-12 auxotrophs can salvage different B-12 building blocks and cooperate to synthesize B-12. A Colwellia sp. synthesizes and releases the activated lower ligand alpha-ribazole, which is used by another B-12 auxotroph, ...
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作者：Leeming, Jack
摘要：Neven Ivea investigates the invasive species in the Adriatic Sea, and works out how to lessen its impact.
