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• Laser fusion success sparks hope of new route to fusion power AI翻译
  作者：Clery, Daniel
• Possible psychedelic therapeutic mechanism AI翻译
  作者：Hess, Evan M.; Gould, Todd D.
  作者单位：University System of Maryland; University of Maryland Baltimore; University System of Maryland; University of Maryland Baltimore; University System of Maryland; University of Maryland Baltimore
• Leveraging IP for AI governance AI翻译
  作者：Schmit, C. D.; Doerr, M. J.; Wagner, J. K.
  作者单位：Texas A&M University System; Texas A&M University College Station; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park
• Menin reads H3K79me2 mark in a nucleosomal context AI翻译
  作者：Lin, Jianwei; Wu, Yiping; Tian, Gaofei; Yu, Daqi; Yang, Eunjeong; Lam, Wai Hei; Liu, Zheng; Jing, Yihang; Dang, Shangyu; Bao, Xiucong; Wong, Jason Wing Hon; Zhai, Yuanliang; Li, Xiang David
  作者单位：University of Hong Kong; Hong Kong University of Science & Technology; Shenzhen Bay Laboratory; University of Hong Kong; University of Hong Kong
  摘要：Methylation of histone H3 lysine-79 (H3K79) is an epigenetic mark for gene regulation in development, cellular differentiation, and disease progression. However, how this histone mark is translated into downstream effects remains poorly understood owing to a lack of knowledge about its readers. We developed a nucleosome-based photoaffinity probe to capture proteins that recognize H3K79 dimethylation (H3K79me2) in a nucleosomal context. In combination with a quantitative proteomics approach, th...
• Comment on Sexual selection promotes giraffoid head-neck evolution and ecological adaptation AI翻译
  作者：Hou, Sukuan; Shi, Qinqin; Benton, Michael J.; Solounias, Nikos
  作者单位：Chinese Academy of Sciences; Institute of Vertebrate Paleontology & Paleoanthropology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; University of Bristol; New York Institute Technology; American Museum of Natural History (AMNH)
  摘要：Wang et al. (Research Articles, 3 June 2022, eabl8316) reported an early Miocene giraffoid that exhibited fierce head-butting behavior and concluded that sexual selection promoted head-neck evolution in giraffoids. However, we argue that this ruminant is not a giraffoid and thus that the hypothesis that sexual selection promoted giraffoid head-neck evolution is not sufficiently supported.
• Ultralow frictional healing explains recurring slow slip events AI翻译
  作者：Shreedharan, Srisharan; Saffer, Demian; Wallace, Laura M.; Williams, Charles
  作者单位：University of Texas System; University of Texas Austin; Utah System of Higher Education; Utah State University; University of Texas System; University of Texas Austin; GNS Science - New Zealand
  摘要：Plate motion on shallow subduction megathrusts is accommodated by a spectrum of tectonic slip modes. However, the frictional properties and conditions that sustain these diverse slip behaviors remain enigmatic. Frictional healing is one such property, which describes the degree of fault restrengthening between earthquakes. We show that the frictional healing rate of materials entrained along the megathrust at the northern Hikurangi margin, which hosts well-characterized recurring shallow slow ...
• Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication AI翻译
  作者：Tsukamoto, Yuta; Hiono, Takahiro; Yamada, Shintaro; Matsuno, Keita; Faist, Aileen; Claff, Tobias; Hou, Jianyu; Namasivayam, Vigneshwaran; vom Hemdt, Anja; Sugimoto, Satoko; Ng, Jin Ying; Christensen, Maria H.; Tesfamariam, Yonas M.; Wolter, Steven; Juranek, Stefan; Zillinger, Thomas; Bauer, Stefan; Hirokawa, Takatsugu; Schmidt, Florian I.; Kochs, Georg; Shimojima, Masayuki; Huang, Yi-Shuian; Pichlmair, Andreas; Kuemmerer, Beate M.; Sakoda, Yoshihiro; Schlee, Martin; Brunotte, Linda; Mueller, Christa E.; Igarashi, Manabu; Kato, Hiroki
  作者单位：University of Bonn; Hokkaido University; Hokkaido University; Hokkaido University; Hokkaido University; University of Munster; University of Bonn; University of Bonn; Japan Institute for Health Security (JIHS); National Institute of Infectious Diseases (NIID); University of Bonn; University of Bonn; University of Bonn; Philipps University Marburg; Aarhus University; University of Tsukuba; University of Tsukuba; National Institute of Advanced Industrial Science & Technology (AIST); University of Bonn; University of Freiburg; University of Freiburg; Academia Sinica - Taiwan; Academia Sinica - Taiwan; Technical University of Munich; German Center for Infection Research; German Center for Infection Research; Hokkaido University
  摘要：Orthomyxo- and bunyaviruses steal the 5' cap portion of host RNAs to prime their own transcription in a process called cap snatching. We report that RNA modification of the cap portion by host 2'-O-ribose methyltransferase 1 (MTr1) is essential for the initiation of influenza A and B virus replication, but not for other cap-snatching viruses. We identified with in silico compound screening and functional analysis a derivative of a natural product from Streptomyces, called trifluoromethyl-tuber...
• Diversity gains in US STEM AI翻译
  作者：[Anonymous]
• Melting glaciers threaten millions downstream AI翻译
  作者：Brainard, Jeffrey
• What no one told me AI翻译
  作者：Mastro, Halley
  作者单位：University of Vermont