作者：Stone, Richard; Ortega, Rodrigo Perez
摘要：Mexican biologist Rodrigo Medellin Legorreta is fighting political headwinds to preserve his country's natural heritage-and his own legacy
作者：Chartrand, Thomas; Dalley, Rachel; Close, Jennie; Goriounova, Natalia A.; Lee, Brian R.; Mann, Rusty; Miller, Jeremy A.; Molnar, Gabor; Mukora, Alice; Alfiler, Lauren; Baker, Katherine; Bakken, Trygve E.; Berg, Jim; Bertagnolli, Darren; Braun, Thomas; Brouner, Krissy; Casper, Tamara; Csajbok, Eva Adrienn; Dee, Nick; Egdorf, Tom; Enstrom, Rachel; Galakhova, Anna A.; Gary, Amanda; Gelfand, Emily; Goldy, Jeff; Hadley, Kristen; Heistek, Tim S.; Hill, Dijon; Jorstad, Nik; Kim, Lisa; Kocsis, Agnes Katalin; Kruse, Lauren; Kunst, Michael; Leon, Gabriela; Long, Brian; Mallory, Matthew; Mcgraw, Medea; Mcmillen, Delissa; Melief, Erica J.; Mihut, Norbert; Ng, Lindsay; Nyhus, Julie; Olah, Gaspar; Ozsvar, Attila; Omstead, Victoria; Peterfi, Zoltan; Pom, Alice; Potekhina, Lydia; Rajanbabu, Ramkumar; Rozsa, Marton; Ruiz, Augustin; Sandle, Joanna; Sunkin, Susan M.; Szots, Ildiko; Tieu, Michael; Toth, Martin; Trinh, Jessica; Vargas, Sara; Vumbaco, David; Williams, Grace; Wilson, Julia; Yao, Zizhen; Barzo, Pal; Cobbs, Charles; Ellenbogen, Richard G.; Esposito, Luke; Ferreira, Manuel; Gouwens, Nathan W.; Grannan, Benjamin; Gwinn, Ryder P.; Hauptman, Jason S.; Jarsky, Tim; Keene, C. Dirk; Ko, Andrew L.; Koch, Christof; Ojemann, Jeffrey G.; Patel, Anoop; Ruzevick, Jacob; Silbergeld, Daniel L.; Smith, Kimberly; Sorensen, Staci A.; Tasic, Bosiljka; Ting, Jonathan T.; Waters, Jack; de Kock, Christiaan P. J.; Mansvelder, Huib D.; Tamas, Gabor; Zeng, Hongkui; Kalmbach, Brian; Lein, Ed S.
作者单位：Allen Institute for Brain Science; Vrije Universiteit Amsterdam; Hungarian Academy of Sciences; Szeged University; University of Washington; University of Washington Seattle; Szeged University; Swedish Medical Center; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle
摘要：Neocortical layer 1 (L1) is a site of convergence between pyramidal-neuron dendrites and feedback axons where local inhibitory signaling can profoundly shape cortical processing. Evolutionary expansion of human neocortex is marked by distinctive pyramidal neurons with extensive L1 branching, but whether L1 interneurons are similarly diverse is underexplored. Using Patch-seq recordings from human neurosurgical tissue, we identified four transcriptomic subclasses with mouse L1 homologs, along wi...
作者：Siletti, Kimberly; Hodge, Rebecca; Albiach, Alejandro Mossi; Lee, Ka Wai; Ding, Song-Lin; Hu, Lijuan; Lonnerberg, Peter; Bakken, Trygve; Casper, Tamara; Clark, Michael; Dee, Nick; Gloe, Jessica; Hirschstein, Daniel; Shapovalova, Nadiya V.; Keene, C. Dirk; Nyhus, Julie; Tung, Herman; Yanny, Anna Marie; Arenas, Ernest; Lein, Ed S.; Linnarsson, Sten
作者单位：Karolinska Institutet; Allen Institute for Brain Science; University of Washington; University of Washington Seattle; Utrecht University; Utrecht University Medical Center
作者：Pan, Qingsong; Yang, Muxin; Feng, Rui; Chuang, Andrew Chihpin; An, Ke; Liaw, Peter K.; Wu, Xiaolei; Tao, Nairong; Lu, Lei
作者单位：Chinese Academy of Sciences; Institute of Metal Research, CAS; Chinese Academy of Sciences; United States Department of Energy (DOE); Oak Ridge National Laboratory; United States Department of Energy (DOE); Argonne National Laboratory; University of Tennessee System; University of Tennessee Knoxville
摘要：Coarse-grained materials are widely accepted to display the highest strain hardening and the best tensile ductility. We experimentally report an attractive strain hardening rate throughout the deformation stage at 77 kelvin in a stable single-phase alloy with gradient dislocation cells that even surpasses its coarse-grained counterparts. Contrary to conventional understanding, the exceptional strain hardening arises from a distinctive dynamic structural refinement mechanism facilitated by the ...
作者：Anggara, Kelvin; Srsan, Laura; Jaroentomeechai, Thapakorn; Wu, Xu; Rauschenbach, Stephan; Narimatsu, Yoshiki; Clausen, Henrik; Ziegler, Thomas; Miller, Rebecca L.; Kern, Klaus
作者单位：Max Planck Society; Eberhard Karls University of Tubingen; University of Copenhagen; University of Oxford; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
摘要：Proteins and lipids decorated with glycans are found throughout biological entities, playing roles in biological functions and dysfunctions. Current analytical strategies for these glycan-decorated biomolecules, termed glycoconjugates, rely on ensemble-averaged methods that do not provide a full view of positions and structures of glycans attached at individual sites in a given molecule, especially for glycoproteins. We show single-molecule analysis of glycoconjugates by direct imaging of indi...
作者：Kim, Chang N.; Shin, David; Wang, Albert; Nowakowski, Tomasz J.
作者单位：University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco
