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作者：Lei, Lihua; Ramdas, Aaditya; Fithian, William
作者单位：Stanford University; Carnegie Mellon University; University of California System; University of California Berkeley
摘要：We propose a general framework based on selectively traversed accumulation rules for interactive multiple testing with generic structural constraints on the rejection set. It combines accumulation tests from ordered multiple testing with data-carving ideas from post-selection inference, allowing highly flexible adaptation to generic structural information. Our procedure defines an interactive protocol for gradually pruning a candidate rejection set, beginning with the set of all hypotheses and...
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作者：Hiabu, M.; Nielsen, J. P.; Scheike, T. H.
作者单位：University of Sydney; City St Georges, University of London; University of Copenhagen
摘要：We consider an extension of Aalen's additive regression model that allows covariates to have effects that vary on two different time scales. The two time scales considered are equal up to a constant for each individual and vary across individuals, such as follow-up time and age in medical studies or calendar time and age in longitudinal studies. The model was introduced in Scheike (2001), where it was solved using smoothing techniques. We present a new backfitting algorithm for estimating the ...
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作者：Dukes, Oliver; Vansteelandt, Stijn
作者单位：Ghent University
摘要：Eliminating the effect of confounding in observational studies typically involves fitting a model for an outcome adjusted for covariates. When, as often, these covariates are high-dimensional, this necessitates the use of sparse estimators, such as the lasso, or other regularization approaches. Naive use of such estimators yields confidence intervals for the conditional treatment effect parameter that are not uniformly valid. Moreover, as the number of covariates grows with the sample size, co...
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作者：Hui, Francis K. C.
作者单位：Australian National University
摘要：Information criteria are commonly used for joint fixed and random effects selection in mixed models. While information criteria are straightforward to implement, a major difficulty in applying them is that they are typically based on maximum likelihood estimates, but calculating such estimates for one candidate mixed model, let alone multiple models, presents a major computational challenge. To overcome this hurdle, we study penalized quasilikelihood estimation and use it as the basis for perf...
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作者：He, Xu
作者单位：Chinese Academy of Sciences; Academy of Mathematics & System Sciences, CAS
摘要：Experimental designs that spread points apart from each other on projections are important for computer experiments, when not necessarily all factors have a substantial influence on the response. We provide a theoretical framework for generating designs that have quasi-optimal separation distance on all the projections and quasi-optimal fill distance on univariate margins. The key is to use special techniques to rotate certain lattices. One such type of design is the class of densest packing-b...
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作者：Na, S.; Kolar, M.; Koyejo, O.
作者单位：University of Chicago; University of Chicago; University of Illinois System; University of Illinois Urbana-Champaign
摘要：Differential graphical models are designed to represent the difference between the conditional dependence structures of two groups, and thus are of particular interest for scientific investigations. Motivated by modern applications, this manuscript considers an extended setting where each group is generated by a latent variable Gaussian graphical model. Due to the existence of latent factors, the differential network is decomposed into sparse and low-rank components, both of which are symmetri...
