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作者：Linderman, Scott W.; Blei, David M.
作者单位：Columbia University; Columbia University
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作者：Bhat, K. Sham; Mebane, David S.; Mahapatra, Priyadarshi; Storlie, Curtis B.
作者单位：United States Department of Energy (DOE); Los Alamos National Laboratory; West Virginia University; United States Department of Energy (DOE); National Energy Technology Laboratory - USA; Mayo Clinic
摘要：Uncertainties from model parameters and model discrepancy from small-scale models impact the accuracy and reliability of predictions of large-scale systems. Inadequate representation of these uncertainties may result in inaccurate and overconfident predictions during scale-up to larger systems. Hence, multiscale modeling efforts must accurately quantify the effect of the propagation of uncertainties during upscaling. Using a Bayesian approach, we calibrate a small-scale solid sorbent model to ...
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作者：Ren, Boyu; Bacallado, Sergio; Favaro, Stefano; Holmes, Susan; Trippa, Lorenzo
作者单位：Harvard University; University of Cambridge; University of Turin; Stanford University
摘要：Human microbiome studies use sequencing technologies to measure the abundance of bacterial species or Operational Taxonomic Units (OTUs) in samples of biological material. Typically the data are organized in contingency tables with OTU counts across heterogeneous biological samples. In the microbial ecology community, ordination methods are frequently used to investigate latent factors or clusters that capture and describe variations of OTU counts across biological samples. It remains importan...
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作者：Zhou, Yong-Dao; Xu, Hongquan
作者单位：Sichuan University; University of California System; University of California Los Angeles
摘要：Central composite designs are widely used in practice for factor screening and building response surface models. We study two classes of newcomposite designs. The first class consists of a two-level factorial design and a three-level orthogonal array; the second consists of a two-level factorial and a three-level definitive screening design. We derive bounds of their efficiencies for estimating all and part of the parameters in a second-order model and obtain some general theoretical results. ...
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作者：He, Xu
作者单位：Chinese Academy of Sciences; Academy of Mathematics & System Sciences, CAS
摘要：We propose a new class of space-filling designs called rotated sphere packing designs for computer experiments. The approach starts from the asymptotically optimal positioning of identical balls that covers the unit cube. Properly scaled, rotated, translated, and extracted, such designs are excellent in maximin distance criterion, low in discrepancy, good in projective uniformity and thus useful in both prediction and numerical integration purposes. We provide a fast algorithm to construct suc...
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作者：Schennach, Susanne M.; Wilhelm, Daniel
作者单位：Brown University; University of London; University College London
摘要：We propose a simple model selection test for choosing among two parametric likelihoods, which can be applied in the most general setting without any assumptions on the relation between the candidate models and the true distribution. That is, both, one or neither is allowed to be correctly specified or misspecified, they may be nested, nonnested, strictly nonnested, or overlapping. Unlike in previous testing approaches, no pretesting is needed, since in each case, the same test statistic togeth...
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作者：Foti, Nicholas J.; Fox, Emily B.
作者单位：University of Washington; University of Washington Seattle
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作者：Handcock, Mark S.
作者单位：University of California System; University of California Los Angeles
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作者：Tao, Ran; Zeng, Donglin; Lin, Dan-Yu
作者单位：Vanderbilt University; University of North Carolina; University of North Carolina Chapel Hill
摘要：In modern epidemiological and clinical studies, the covariates of interest may involve genome sequencing, biomarker assay, or medical imaging and thus are prohibitively expensive to measure on a large number of subjects. A cost-effective solution is the two-phase design, under which the outcome and inexpensive covariates are observed for all subjects during the first phase and that information is used to select subjects for measurements of expensive covariates during the second phase. For exam...
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作者：Raftery, Adrian E.
作者单位：University of Washington; University of Washington Seattle
