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作者:Chen, Qiushi; Ayer, Turgay; Chhatwal, Jagpreet
作者单位:Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; University System of Georgia; Georgia Institute of Technology; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital
摘要:Hepatocellular carcinoma (HCC) is the most common type of liver cancer and the fastest-growing cause of cancer-related deaths in the United States. Most HCC cases are attributed to chronic hepatitis C virus infection, which affects nearly 3 million Americans and 100 million people globally. Although surveillance for HCC m hepatitis C patients can improve survival, the optimal surveillance policies remain unknown. In this study, we develop a mixed-integer programming (MlP)-based framework to sy...
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作者:Chen, Xin; Gao, Xiangyu; Pang, Zhan
作者单位:University of Illinois System; University of Illinois Urbana-Champaign; Chinese University of Hong Kong; City University of Hong Kong
摘要:A common technical challenge encountered in many operations management models is that decision variables are truncated by some random variables and the decisions are made before the values of these random variables are realized, leading to non-convex minimization problems. To address this challenge, we develop a powerful transformation technique that converts a nonconvex minimization problem to an equivalent convex minimization problem. We show that such a transformation enables us to prove th...
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作者:Lee, Joosung
作者单位:University of Edinburgh
摘要:We introduce a new noncooperative multilateral bargaining model for network-restricted environments in which players can bargain only with their neighbors. The main theorem characterizes a condition on network structures for efficient equilibria. If the underlying network is either complete or circular, an efficient stationary subgame perfect equilibrium exists for all discount factors-all the players always try to reach an agreement as soon as practicable, and hence no strategic delay occurs....
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作者:Chen, Shi; Moinzadeh, Kamran
作者单位:University of Washington; University of Washington Seattle
摘要:We study an inventory system involving a contractor, who provides quotations of delivery times to customers, and suppliers, who stock prefabricated modules that the contractor will use to complete orders. The customers' decisions on whether to wait or leave depend on the quotations. This is an assembly system with partial lost sales, where the interaction between the quotation policy and the inventory policy is complicated. We consider either a uniform or an adaptive quotation policy and eithe...
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作者:Petersen, Niels Christian
作者单位:University of Southern Denmark
摘要:This paper is concerned with optimal directions in the directional distance function in data envelopment analysis. It is shown that the vector pointing in the direction that minimizes the Euclidean distance between the input-output vector (X-0, Y-0) and the efficient frontier, the input isoquant reflecting output Y-0, or the output isoquant reflecting input X-0 is optimal, because the corresponding vector of virtual multipliers defines the relative prices that maximize profit, cost, or revenue...
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作者:Feng, Qi; Shanthikumar, J. George
作者单位:Purdue University System; Purdue University
摘要:We study the role of bargaining in a firm's sequential selling process. The seller firm under consideration sequentially sells a fixed amount of stock to a random arrival stream of potential buyers who are heterogeneous in product valuation. Based on the stock level and the time to the end of the selling season, the seller may dynamically choose either to post a take-it-or-leave-it price or to engage in bargaining with an arriving buyer. We introduce a stochastic order, called the scaled prici...
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作者:Emadi, Seyed Morteza; Swaminathan, Jayashankar M.
作者单位:University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine
摘要:Designing modern call centers requires an understanding of callers' patience and abandonment behavior. Using a Cox regression analysis, we show that callers' abandonment behavior may differ based on their contact history, and changes across their different contacts. We control for caller heterogeneity using a two-step grouped-fixed effect method. This analysis shows that differences in callers' abandonment behavior are not only driven by their heterogeneity but also by differences in their bel...
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作者:Klausen, Jytte; Marks, Christopher E.; Zaman, Tauhid
作者单位:Brandeis University; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT)
摘要:Online extremists' use of social media poses a new form of threat to the general public. These extremists range from cyberbullies to terrorist organizations. Social media providers often suspend the extremists' accounts in response to user complaints. However, extremist users can simply create new accounts and continue their activities. In this work we present a new set of operational capabilities to address the threat posed by online extremists in social networks. We use thousands of Twitter ...
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作者:Xu, Zhou; Lee, Chung-Yee
作者单位:Hong Kong Polytechnic University; Hong Kong University of Science & Technology
摘要:We study a continuous berth allocation problem, where incoming vessels need to be assigned a mooring time as well as a berth location on a quay. It is a crucial element in port planning to achieve quick turnaround time for vessels. To solve this problem, many solution methods have been developed in the literature. However, gaps between the best-known lower and upper bounds on its optimal solutions are far from close. In this paper, we propose new and more effective solution methods for this im...
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作者:Zeng, Yun; Chaintreau, Augustin; Towsley, Don; Xia, Cathy H.
作者单位:University System of Ohio; Ohio State University; Columbia University; University of Massachusetts System; University of Massachusetts Amherst
摘要:Parallel and distributed processing systems have expanded in size as technology advances in cloud computing and big data analytics. A critical issue concerns throughput scalability: whether throughput decreases to zero as the systems scale in size and capabilities. We model parallel and distributed processing systems as fork and join queueing networks with blocking (FJQN/Bs). Such networks can have arbitrary topology, arbitrary initial state, and generally distributed service times. We propose...