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作者：Wu, JT; Wein, LM; Perelson, AS
作者单位：United States Department of Energy (DOE); Los Alamos National Laboratory; University System of Georgia; Georgia Institute of Technology; Stanford University
摘要：The World Health Organization (WHO) recommends which strains of influenza to include in each year's vaccine to countries around the globe. The current WHO strategy attempts to match the vaccine strains with the expected upcoming epidemic strains, a strategy we refer to as the follow policy. The recently proposed antigenic distance hypothesis suggests that vaccine efficacy can be enhanced by taking into account the antigenic histories of vaccinees. To assess the potential benefit of history-bas...
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作者：Lambert, TJ III; Epelman, MA; Smith, RL
作者单位：Nevada System of Higher Education (NSHE); Truckee Meadows Community College; University of Michigan System; University of Michigan
摘要：In this paper, we investigate the properties of the sampled version of the fictitious play algorithm, familiar from game theory, for games with identical payoffs, and propose a heuristic based on fictitious play as a solution procedure for discrete optimization problems of the form max {u(y): y (y(1),..., y(n)) is an element of y(1) x(...)x y(n)} i.e., in which the feasible region is a Cartesian product of finite sets y(i), i is an element of N = {1,..., n}. The contributions of this paper are...
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作者：Goycoolea, M; Murray, AT; Barahona, F; Epstein, R; Weintraub, A
作者单位：University System of Georgia; Georgia Institute of Technology; University System of Ohio; Ohio State University; International Business Machines (IBM); IBM USA; Universidad de Chile
摘要：We consider a spatial problem arising in forest harvesting. For regulatory reasons, blocks harvested should not exceed a certain total area, typically 49 hectares. Traditionally, this problem, called the adjacency problem, has been approached by forming a priori blocks from basic cells of 5 to 25 hectares and solving the resulting mixed-integer program. Superior solutions can be obtained by including the construction of blocks in the decision process. The resulting problem is far more complex ...
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作者：Yang, H; Ye, M; Tang, WHC; Wong, SC
作者单位：Hong Kong University of Science & Technology; University of Hong Kong
摘要：This paper presents a spatially aggregated multiperiod taxi service model with endogenous service intensity. The whole day service period is divided into a number of subperiods; during each subperiod, taxi supply and customer demand characteristics are assumed to be uniform. Customer demand is period-specific and described as a function of waiting time and taxi fare. Taxi operating cost for each work shift consists of two components: one component a function of total service time and the other...
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作者：Andradóttir, S; Ayhan, H
作者单位：University System of Georgia; Georgia Institute of Technology
摘要：For a Markovian queueing network with two stations in tandem, finite intermediate buffer, and M flexible servers, we study how the servers should be assigned dynamically to stations to obtain optimal long-run average throughput. We assume that each server can work on only one job at a time, that several servers can work together on a single job, and that the travel times between stations are negligible. Under these assumptions, we completely characterize the optimal policy for systems with thr...
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作者：Chod, J; Rudi, N
作者单位：Boston College; University of Rochester
摘要：This article studies two types of flexibility used by firms to better respond to uncertain market conditions: resource flexibility and responsive pricing. We consider a situation in which a single flexible resource can be used to satisfy two distinct demand classes. While the resource capacity must be decided based on uncertain demand functions, the resource allocation as well as the pricing decision are made based on the realized demand functions. We characterize the effects of two key driver...
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作者：Biller, B; Nelson, BL
作者单位：Carnegie Mellon University; Northwestern University
摘要：Providing accurate and automated input-modeling support is one of the challenging problems in the application of computer simulation of stochastic systems. The models incorporated in current input-modeling software packages often fall short because they assume independent and identically distributed processes, even though dependent time-series input processes occur naturally in the simulation of many real-life systems. Therefore, this paper introduces a statistical methodology for fitting stoc...
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作者：Epelman, MA; Pollock, S; Netter, B; Low, BS
作者单位：University of Michigan System; University of Michigan; Yale University; University of Michigan System; University of Michigan
摘要：No good formal arguments exist for a central question in biology: Why, in species that have sexual reproduction, are there usually only males and females? We present a nonlinear optimization model that supports the conclusion that having only two sexes maximizes long-run viability.
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作者：Fridgeirsdottir, K; Chiu, S
作者单位：University of London; London Business School; Stanford University
摘要：In this note, we show that the expected delay cost for a G/G/1 queue is not necessarily convex in the arrival rate as sometimes claimed in the literature. We can prove, however, that the total expected delay cost rate is convex in the arrival rate. This cost rate is often of interest when designing queueing systems.
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作者：Sodhi, MS
作者单位：City St Georges, University of London
摘要：Dynamic linear programming (LP) models for asset-liability management (ALM) are quite powerful and flexible but face two challenges: (1) many modeling choices, not all consistent with one another or with finance theory, and (2) solution difficulties due to the large number of scenarios obtained from standard interest-rate models. We first survey these modeling choices with a view to help researchers make self-consistent choices. Next, we review how the dynamic LP model for ALM and the represen...
