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作者：Meng, Fanwen; Qi, Jin; Zhang, Meilin; Ang, James; Chu, Singfat; Sim, Melvyn
作者单位：Hong Kong University of Science & Technology; National University of Singapore
摘要：The admission of emergency patients in a hospital is unscheduled, urgent, and takes priority over elective patients, who are usually scheduled several days in advance. Hospital beds are a critical resource, and the management of elective admissions by enforcing quotas could reduce incidents of shortfall. We propose a distributionally robust optimization approach for managing elective admissions to determine these quotas. Based on an ambiguous set of probability distributions, we propose an opt...
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作者：Prekopa, Andras; Unuvar, Merve
作者单位：Rutgers University System; Rutgers University New Brunswick; International Business Machines (IBM); IBM USA
摘要：Single commodity networks are considered, where demands at the nodes are random. The problem is to find minimum cost optimal built in capacities at the nodes and arcs subject to the constraint that all demands should be met on a prescribed probability level (reliability constraint) and some deterministic constraints should be satisfied. The reliability constraint is formulated in terms of the Gale-Hoffman feasibility inequalities, but their number is reduced by elimination technique. The conce...
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作者：Goh, Joel; Bjarnadottir, Margret V.; Bayati, Mohsen; Zenios, Stefanos A.
作者单位：Harvard University; University System of Maryland; University of Maryland College Park; Stanford University
摘要：Postmarketing drug surveillance is the process of monitoring the adverse events of pharmaceutical or medical devices after they are approved by the appropriate regulatory authorities. Historically, such surveillance was based on voluntary reports by medical practitioners, but with the widespread adoption of electronic medical records and comprehensive patient databases, surveillance systems that utilize such data are of considerable interest. Unfortunately, existing methods for analyzing the d...
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作者：Pinker, Edieal J.
作者单位：Yale University
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作者：Peura, Heikki; Bunn, Derek W.
作者单位：University of London; London Business School; University of London; London Business School
摘要：Peak producers of nonstorable products, such as electricity, provide crucial flexible operating capacity to respond to infrequent and transient high demand periods. Faced with these uncertain revenue-earning opportunities, despite often having significant price-setting power, they need to profit from a limited number of pricing decisions in order to meet financial targets for viability. We study the repeated interaction between peak producers with a model that captures both the uncertainty in ...
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作者：Wu, Shining; Liu, Qian; Zhang, Rachel Q.
作者单位：Hong Kong Polytechnic University; Hong Kong University of Science & Technology
摘要：We consider a retailer that sells the same or different versions of the product season after season. At the beginning of each season (stage 1), the retailer places an order and sells the product at the full price. As the sales unfold, the retailer has an opportunity to mark down the price (stage 2), which creates an incentive for strategic consumers to delay their purchases for price discount. However, consumers do not know the markdown price exactly when they time their purchases; instead, th...
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作者：Jacquillat, Alexandre; Odoni, Amedeo R.
作者单位：Massachusetts Institute of Technology (MIT); Carnegie Mellon University; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT)
摘要：Most flight delays are created by imbalances between demand and capacity at the busiest airports. Absent large increases in capacity, airport congestion can only be mitigated through scheduling interventions or improved capacity utilization. This paper presents an integrated approach that jointly optimizes the airport's flight schedule at the strategic level and the utilization of airport capacity at the tactical level, subject to scheduling, capacity, and delay-reduction constraints. The capa...
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作者：Doan, Xuan Vinh; Li, Xiaobo; Natarajan, Karthik
作者单位：University of Warwick; University of Warwick; University of Minnesota System; University of Minnesota Twin Cities; Singapore University of Technology & Design
摘要：In this paper, we develop a distributionally robust portfolio optimization model where the robustness is across different dependency structures among the random losses. For a Frechet class of discrete distributions with overlapping marginals, we show that the distributionally robust portfolio optimization problem is efficiently solvable with linear programming. To guarantee the existence of a joint multivariate distribution consistent with the overlapping marginal information, we make use of a...
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作者：Jiang, Daniel R.; Powell, Warren B.
作者单位：Princeton University
摘要：Many sequential decision problems can be formulated as Markov decision processes (MDPs) where the optimal value function (or cost-to-go function) can be shown to satisfy a monotone structure in some or all of its dimensions. When the state space becomes large, traditional techniques, such as the backward dynamic programming algorithm (i. e., backward induction or value iteration), may no longer be effective in finding a solution within a reasonable time frame, and thus we are forced to conside...
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作者：Helm, Jonathan E.; Lavieri, Mariel S.; Van Oyen, Mark P.; Stein, Joshua D.; Musch, David C.
作者单位：Indiana University System; IU Kelley School of Business; Indiana University Bloomington; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan
摘要：In managing chronic diseases such as glaucoma, the timing of periodic examinations is crucial, as it may significantly impact patients' outcomes. We address the question of when to monitor a glaucoma patient by integrating a dynamic, stochastic state space system model of disease evolution with novel optimization approaches to predict the likelihood of progression at any future time. Information about each patient's disease state is learned sequentially through a series of noisy medical tests....
