Fundamentals of wound care for amputation prevention

• 成果类型: Review
• 署名作者: Almeida, Beatriz Moschiar; Evans, Robyn; Kayssi, Ahmed
• 署名单位: University of Toronto; University of Toronto; Womens College Hospital; University of Toronto; University of Toronto; University of Toronto; Sunnybrook Health Science Center; Sunnybrook Research Institute
• 刊物名称: SEMINARS IN VASCULAR SURGERY
• ISSN/ISSBN: 0895-7967; 1558-4518
• DOI: 10.1053/j.semvascsurg.2025.01.001
• 发表日期: 2025-03
• 页码: 54-63
• 关键词: Diabetic foot ulcer; Critical limb-threatening ischemia; Wound care; amputation; Limb preservation; DIABETIC FOOT ULCERS; PERIPHERAL ARTERY-DISEASE; follow-up; management; RISK; OSTEOMYELITIS.; debridement; infection; ischemia; therapy

摘要

The initial skin breakdown and subsequent healing processes are complex and influenced by various parameters, including systemic factors, infectious bioburden, and perfusion. Vascular wounds comprise inadequate inflow (due to peripheral artery disease), microvascular damage (result of diabetes mellitus), or vasoconstriction. Normal healing of acute wounds occurs in a sequence of defined stages; however, if a dysregulated inflammatory state ensues, it is classified as chronic. Both chronic and vascular wounds carry an increased risk of amputation. Therefore, holistic wound care is crucial in preventing limb loss. This review outlines a systematic approach to wound assessment and examines the latest recommendations for managing vascular wounds, focusing on strategies for preventing amputations. (c) 2025 The Author(s). Published by Elsevier Inc. ( http://creativecommons.org/licenses/by-nc-nd/4.0/ )