ON THE REGRESSION-ANALYSIS OF MULTIVARIATE FAILURE TIME DATA
成果类型：
Article
署名作者：
PRENTICE, RL; WILLIAMS, BJ; PETERSON, AV
署名单位：
Gonzaga University
刊物名称：
BIOMETRIKA
ISSN/ISSBN：
0006-3444
DOI：
10.1093/biomet/68.2.373
发表日期：
1981
页码：
373379
关键词：
摘要：
Analysis of regression effects when individual study subjects may experience multiple failures [i.e., time sequence of asthmatic attacks, epileptic seizures, infection episodes, tumor diagnoses, tumor recurrences or bleeding incidents in individual patients] was undertaken. The proposed methods are useful when there are a large number of study subjects. Two general classes of regression models are considered in order to relate the hazard or intensity function to covariates and to preceding failure time history. Both models are of a stratified proportional hazards type. One model includes base-line intensity functions that are arbitrary as a function of time from the beginning of the study, while the other includes baseline intensity functions that are arbitrary as a function of time from the study subject''s immediately preceding failure. Partial likelihood functions are derived for the regression coefficients. Generalizations and illustrations are given.
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