EFFICIENT SEQUENTIAL DESIGNS FOR DESTRUCTIVE LIFE TESTING WITH APPLICATION TO ANIMAL SERIAL SACRIFICE EXPERIMENTS
成果类型：
Article
署名作者：
BERGMAN, SW; TURNBULL, BW
署名单位：
Cornell University
刊物名称：
BIOMETRIKA
ISSN/ISSBN：
0006-3444
发表日期：
1983
页码：
305314
关键词：
摘要：
The scheduling of inspection times in a life testing experiment when testing is destructive is considered. One application is to animal carcinogenicity tests where it is desired to find serial sacrifice schedules which allow efficient estimation of the onset time distribution for a tumor which is assumed irreversible, nonlethal and occult, i.e. detectable only at death. A class of designs are introduced and their properties are discussed. It is shown how to construct a design in this class that is asymptotically efficient. Tables of relative efficiencies are presented for the case of exponentially distributed failure times and test population sizes of 50 and 200. Some extensions of the theory are discussed.